Linked Life Data

10335461

Source:http://linkedlifedata.com/resource/pubmed/id/10335461

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1999-7-14
pubmed:abstractText
Using data of a case-control study conducted in Italy between 1992 and 1996 on 1225 cases of colon cancer and 4154 controls, we have evaluated the effect of selected established risk factors in subjects with, and in those without, familial propensity (134 cases, 146 controls); there were non-significant associations between education and meal frequency and colon cancer risk. Physical activity, high energy and low vegetable intake were significantly related to colon cancer risk in subjects without familial predisposition, but showed no relationship in those with family history of colorectal cancer: the ORs were 1.1 for the lowest level of physical activity, 0.7 for the highest tertile of energy intake, and 1.0 for the lowest one of vegetable intake. These findings would suggest that genetic predisposition can make the influence of environmental factors for defining the risk of colon cancer weak and/or difficult to estimate.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0959-8278
pubmed:author
pubmed:issnType
Print
pubmed:volume
8
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
147-50
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1999
pubmed:articleTitle
Interaction between selected environmental factors and familial propensity for colon cancer.
pubmed:affiliation
Istituto di Ricerche Famacologiche Mario Negri, Milan, Italy.
pubmed:publicationType
Journal Article