Source:http://linkedlifedata.com/resource/pubmed/id/10327279
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
1999-8-2
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pubmed:abstractText |
Familial combined hyperlipidemia (FCHL) is a complex genetic disorder of unknown etiology. Recently, 'modifier' genes of the FCHL phenotype, such as the apolipoprotein AI-CIII-AIV gene cluster and LPL, have been identified in several populations. A 'major' gene for FCHL has been identified in a Finnish isolate which maps to a region syntenic to murine chromosome 3 where a locus for combined hyperlipidemia has been identified. We review these and other recent studies which indicate that FCHL is genetically heterogeneous.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
0957-9672
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
10
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
113-22
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pubmed:dateRevised |
2010-11-18
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pubmed:meshHeading |
pubmed-meshheading:10327279-Age Factors,
pubmed-meshheading:10327279-Animals,
pubmed-meshheading:10327279-Disease Models, Animal,
pubmed-meshheading:10327279-Finland,
pubmed-meshheading:10327279-Genetic Linkage,
pubmed-meshheading:10327279-Humans,
pubmed-meshheading:10327279-Hyperlipidemia, Familial Combined,
pubmed-meshheading:10327279-Insulin Resistance,
pubmed-meshheading:10327279-Mice,
pubmed-meshheading:10327279-Models, Biological,
pubmed-meshheading:10327279-Phenotype
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pubmed:year |
1999
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pubmed:articleTitle |
Novel genes for familial combined hyperlipidemia.
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pubmed:affiliation |
Department of Microbiology and Molecular Genetics, University of California, Los Angeles 90095-1679, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Review,
Research Support, Non-U.S. Gov't
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