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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
5-6
|
| pubmed:dateCreated |
1977-7-23
|
| pubmed:abstractText |
The growth of experimental tumors was found to involve an intensification of acetylation of sulphadimidine. Inhibition of carcinosarcoma Walker-256 by 88% and sarcoma-180 by 36% on treatment with 60 mg/kg body weight of hydrazine sulphate was followed by decreases in the rate of acetylation of 39.4 and 29.4%, respectively. When treatment failed to suppress tumor growth (sarcoma-45), acetylation level showed no decrease. The results point to a correlation between growth of tumors and their inhibition on the one hand and the level of acetylation on the other.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:issn |
0030-2414
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
33
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
219-21
|
| pubmed:dateRevised |
2006-11-15
|
| pubmed:meshHeading |
pubmed-meshheading:1026855-Acetylation,
pubmed-meshheading:1026855-Acetyltransferases,
pubmed-meshheading:1026855-Animals,
pubmed-meshheading:1026855-Carcinoma 256, Walker,
pubmed-meshheading:1026855-Female,
pubmed-meshheading:1026855-Hydrazines,
pubmed-meshheading:1026855-Mice,
pubmed-meshheading:1026855-Neoplasm Transplantation,
pubmed-meshheading:1026855-Rats,
pubmed-meshheading:1026855-Sulfamethazine,
pubmed-meshheading:1026855-Transplantation, Homologous
|
| pubmed:year |
1976
|
| pubmed:articleTitle |
On the relationship between the activity of acetylation, growth of experimental tumors and efficacy of their suppression by hydrazine sulphate.
|
| pubmed:publicationType |
Journal Article
|