Linked Life Data

1023867

Source:http://linkedlifedata.com/resource/pubmed/id/1023867

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5-6
pubmed:dateCreated
1977-5-20
pubmed:abstractText
Ejaculated spermatozoa from rams given intramuscular injections of alpha-chlorohydrin (25 mg/kg, daily for 5 days) were studied. Respiratory and glycolytic activity of the spermatozoa was almost entirely suppressed within 1 day and motility had decreased within 4 days of the first injection. Morphologically abnormal spermatozoa appeared in ejaculates after 2 weeks. The most common abnormality was an increase in the number of spermatozoa with looped or bent tails. There was little change in the fructose or amino acid concentration of the seminal plasma. All effects of alpha-chlorohydrin were fully reversible. It is suggested that the initial primary mode of action of alpha-chlorohydrin is to disrupt the metabolism of spermatozoa in the cauda epididymis.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0004-9417
pubmed:author
pubmed:issnType
Print
pubmed:volume
29
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
545-55
pubmed:dateRevised
2003-11-14
pubmed:meshHeading
pubmed:year
1976
pubmed:articleTitle
Disruption of the metabolism, motility and morphology of spermatozoa by injection of alpha-chlorohydrin into rams.
pubmed:publicationType
Journal Article