Linked Life Data

10235655

Source:http://linkedlifedata.com/resource/pubmed/id/10235655

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1999-6-24
pubmed:abstractText
The treatment of epilepsies remains far from adequate primarily due to inadequate understanding of the pathophysiology of seizures. The conventional approach for research into epilepsy has been study of factors responsible for initiation of seizures. However, now attention is being drawn to the spontaneous and abrupt arrest of seizures which suggests a distinct possibility of activation of an endogenous anticonvulsant mechanism(s), which may be targeted in future for controlling seizures. Of the various endogenous anticonvulsant mechanisms, the concept of an endogenous anticonvulsant substance has gained much experimental support and, many potential candidates have been postulated. Of these adenosinergic system appears to be the most promising. This review discusses the possible role of adenosinergic system in seizures, in relation to the available antiepileptic drugs and its therapeutic implications.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0019-5499
pubmed:author
pubmed:issnType
Print
pubmed:volume
41
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
329-43
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1997
pubmed:articleTitle
Adenosinergic system as an endogenous anticonvulsant mechanism.
pubmed:affiliation
Department of Pharmacology, All India Institute of Medical Sciences, New Delhi.
pubmed:publicationType
Journal Article, Review