Source:http://linkedlifedata.com/resource/pubmed/id/10231597
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
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pubmed:dateCreated |
1999-7-19
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pubmed:abstractText |
Changes in dehydrogenase activity of some continuous cell lines were studied during the response to acute infection in vitro with HIV-1 variants having different biological features. Soon after infection, the dehydrogenase activity of infected cells increased, and this increase was greater and more prolonged with the HIV-1 r/h variant than with the HIV-1 s/l variant. Later stages showed decreased dehydrogenase activity of HIV-1-infected cells compared to the noninfected control; this is a manifestation of the cytodestructive effect of the virus. The changes increased monotonously (but not in direct proportion) with an increase in the infecting dose.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
0006-2979
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
64
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
431-6
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:10231597-Cell Line,
pubmed-meshheading:10231597-HIV Core Protein p24,
pubmed-meshheading:10231597-HIV Infections,
pubmed-meshheading:10231597-HIV Reverse Transcriptase,
pubmed-meshheading:10231597-HIV-1,
pubmed-meshheading:10231597-Humans,
pubmed-meshheading:10231597-Monocytes,
pubmed-meshheading:10231597-Oxidoreductases
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pubmed:year |
1999
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pubmed:articleTitle |
Dehydrogenase activity of infected cells and biological properties of HIV-1 variants.
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pubmed:affiliation |
Ivanovsky Institute of Virology, Russian Academy of Medical Sciences, Moscow, 123098, Russia.
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pubmed:publicationType |
Journal Article
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