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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
5
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pubmed:dateCreated |
1999-5-18
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pubmed:abstractText |
Hemodynamic instability and generalized organ dysfunction are common after cardiopulmonary bypass in human beings. Previous studies have suggested that alterations of nitric oxide metabolism may be associated with this impaired function. Using a canine model we tested whether nitric oxide synthase activity is increased after cardiopulmonary bypass. We also tested whether administration of a nitric oxide donor can influence nitric oxide synthase activity after cardiopulmonary bypass.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
0022-5223
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
117
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1009-16
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:10220697-Animals,
pubmed-meshheading:10220697-Antigens, CD18,
pubmed-meshheading:10220697-Blood Gas Analysis,
pubmed-meshheading:10220697-Cardiopulmonary Bypass,
pubmed-meshheading:10220697-Coronary Vessels,
pubmed-meshheading:10220697-Disease Models, Animal,
pubmed-meshheading:10220697-Dogs,
pubmed-meshheading:10220697-Glutathione,
pubmed-meshheading:10220697-Hemodynamics,
pubmed-meshheading:10220697-Infusions, Intravenous,
pubmed-meshheading:10220697-Intraoperative Period,
pubmed-meshheading:10220697-Myocardium,
pubmed-meshheading:10220697-Neutrophils,
pubmed-meshheading:10220697-Nitric Oxide Synthase,
pubmed-meshheading:10220697-Nitric Oxide Synthase Type II,
pubmed-meshheading:10220697-Nitroso Compounds,
pubmed-meshheading:10220697-Platelet Aggregation Inhibitors,
pubmed-meshheading:10220697-Postoperative Complications,
pubmed-meshheading:10220697-Random Allocation,
pubmed-meshheading:10220697-S-Nitrosoglutathione
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pubmed:year |
1999
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pubmed:articleTitle |
Increased nitric oxide synthase activity after canine cardiopulmonary bypass is suppressed by s-nitrosoglutathione.
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pubmed:affiliation |
Departments of Medicine and Pharmacology, University of Alberta, Edmonton, Canada.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
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