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rdf:type |
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lifeskim:mentions |
umls-concept:C0017262,
umls-concept:C0024299,
umls-concept:C0162638,
umls-concept:C0185117,
umls-concept:C0205099,
umls-concept:C0220901,
umls-concept:C0439682,
umls-concept:C0441766,
umls-concept:C0449774,
umls-concept:C1332391,
umls-concept:C1522609,
umls-concept:C1554112,
umls-concept:C2911684
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pubmed:issue |
1
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pubmed:dateCreated |
1999-5-6
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pubmed:abstractText |
The prognostic significance of spontaneous levels of apoptosis and Bcl-2, Bax, and Bcl-x protein expression in follicular center lymphoma (FCL) is unknown. The objectives of this retrospective study were (1) to investigate the relationship between pretreatment apoptosis levels and long-term treatment outcome in patients with Stage I and II FCL; (2) to define the incidence and patterns of Bax and Bcl-x protein expression in human FC; and (3) to determine the relationship of Bcl-2, Bax, and Bcl-x expression with spontaneous apoptosis levels and clinical outcome in localized FCL.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
0360-3016
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pubmed:author |
pubmed-author:AndersenMM,
pubmed-author:BesaP CPC,
pubmed-author:BrisbaySS,
pubmed-author:CabanillasFF,
pubmed-author:LogsdonM DMD,
pubmed-author:McDonnellT JTJ,
pubmed-author:MilasLL,
pubmed-author:MiraO JOJ,
pubmed-author:PalN KNK,
pubmed-author:PetersL JLJ,
pubmed-author:PughW CWC,
pubmed-author:StephensL CLC
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pubmed:issnType |
Print
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pubmed:day |
1
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pubmed:volume |
44
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
19-29
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:10219790-Analysis of Variance,
pubmed-meshheading:10219790-Apoptosis,
pubmed-meshheading:10219790-Cohort Studies,
pubmed-meshheading:10219790-Female,
pubmed-meshheading:10219790-Gene Expression,
pubmed-meshheading:10219790-Genes, bcl-2,
pubmed-meshheading:10219790-Humans,
pubmed-meshheading:10219790-Lymphoma, Follicular,
pubmed-meshheading:10219790-Male,
pubmed-meshheading:10219790-Middle Aged,
pubmed-meshheading:10219790-Mitotic Index,
pubmed-meshheading:10219790-Neoplasm Proteins,
pubmed-meshheading:10219790-Neoplasm Staging,
pubmed-meshheading:10219790-Prognosis,
pubmed-meshheading:10219790-Proto-Oncogene Proteins,
pubmed-meshheading:10219790-Proto-Oncogene Proteins c-bcl-2,
pubmed-meshheading:10219790-Retrospective Studies,
pubmed-meshheading:10219790-Treatment Outcome,
pubmed-meshheading:10219790-bcl-2-Associated X Protein,
pubmed-meshheading:10219790-bcl-X Protein
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pubmed:year |
1999
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pubmed:articleTitle |
Apoptosis and the Bcl-2 gene family -- patterns of expression and prognostic value in stage I and II follicular center lymphoma.
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pubmed:affiliation |
Department of Radiation Oncology, The University of Texas M. D. Anderson Cancer Center, Houston 77030, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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