Source:http://linkedlifedata.com/resource/pubmed/id/10218855
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
7
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pubmed:dateCreated |
1999-5-13
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pubmed:abstractText |
We report the case of a 32-year-old patient with ALL who developed autoimmune thrombocytopenia 2 months following allogeneic bone marrow transplantation. An IgM autoantibody against the platelet glycoprotein Ib/IX complex was observed. Treatment with high-dose steroids and intravenous immunoglobulin G failed to produce any benefit and the thrombocytopenia led to fatal gastrointestinal haemorrhage. The possible factors contributing to post-allograft thrombocytopenia and potential management strategies are discussed.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
0268-3369
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
23
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
739-41
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:10218855-Adult,
pubmed-meshheading:10218855-Autoantibodies,
pubmed-meshheading:10218855-Autoimmune Diseases,
pubmed-meshheading:10218855-Bone Marrow Transplantation,
pubmed-meshheading:10218855-Fatal Outcome,
pubmed-meshheading:10218855-Humans,
pubmed-meshheading:10218855-Immunoglobulin M,
pubmed-meshheading:10218855-Male,
pubmed-meshheading:10218855-Platelet Glycoprotein GPIb-IX Complex,
pubmed-meshheading:10218855-Thrombocytopenia,
pubmed-meshheading:10218855-Tissue Donors
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pubmed:year |
1999
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pubmed:articleTitle |
A fatal case of autoimmune thrombocytopenia with an IgM anti-GPIb/IX following one antigen mismatched unrelated donor bone marrow transplantation.
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pubmed:affiliation |
Department of Haematology, University College London Hospitals, UK.
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pubmed:publicationType |
Journal Article,
Case Reports
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