Source:http://linkedlifedata.com/resource/pubmed/id/10214763
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
6
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pubmed:dateCreated |
1999-5-12
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pubmed:abstractText |
The authors report high intrathecal release of tumor necrosis factor alpha (TNF-alpha) and interleukin (IL)-1beta in five patients with sporadic or new-variant Creutzfeldt-Jakob disease (CJD) without activation of the humoral or lymphocytic immune responses. Increased release of TNF-alpha and IL-1beta was also detected in some patients with progressive dementias. CJD is associated with a local cerebral host response that involves the release of proinflammatory cytokines.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
0028-3878
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
12
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pubmed:volume |
52
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1289-91
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading | |
pubmed:year |
1999
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pubmed:articleTitle |
Heightened intrathecal release of proinflammatory cytokines in Creutzfeldt-Jakob disease.
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pubmed:affiliation |
Department of Neurology, Guy's Hospital, London, England. m.sharief@umds.ac.uk
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pubmed:publicationType |
Journal Article
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