rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
14
|
pubmed:dateCreated |
1999-5-6
|
pubmed:abstractText |
Endothelium-dependent dilator responses mediated by NO and endothelium-derived hyperpolarizing factor (EDHF) are altered in arteriosclerosis and sepsis. The possibility that proinflammatory mediators that stimulate the expression of inducible NO synthase (NOS II) affect the generation of EDHF was examined in isolated arteries.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
AIM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Apr
|
pubmed:issn |
1524-4539
|
pubmed:author |
|
pubmed:issnType |
Electronic
|
pubmed:day |
13
|
pubmed:volume |
99
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
1878-84
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:10199886-Animals,
pubmed-meshheading:10199886-Arteries,
pubmed-meshheading:10199886-Biological Factors,
pubmed-meshheading:10199886-Cells, Cultured,
pubmed-meshheading:10199886-Cyclic GMP,
pubmed-meshheading:10199886-Cytochrome P-450 Enzyme System,
pubmed-meshheading:10199886-Endothelium, Vascular,
pubmed-meshheading:10199886-Inflammation Mediators,
pubmed-meshheading:10199886-Nitric Oxide,
pubmed-meshheading:10199886-Rabbits,
pubmed-meshheading:10199886-Rats,
pubmed-meshheading:10199886-Swine,
pubmed-meshheading:10199886-Vasodilation
|
pubmed:year |
1999
|
pubmed:articleTitle |
Proinflammatory mediators chronically downregulate the formation of the endothelium-derived hyperpolarizing factor in arteries via a nitric oxide/cyclic GMP-dependent mechanism.
|
pubmed:affiliation |
Institut für Kardiovaskuläre Physiologie und Institut für Anaesthesiologie, Klinikum der J.W.G.-Universität, Frankfurt/Main, Germany.
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|