Linked Life Data

10197159

Source:http://linkedlifedata.com/resource/pubmed/id/10197159

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1999-4-19
pubmed:abstractText
The vestigial (vg) gene of Drosophila melanogaster encodes a novel nuclear protein which is required for wing formation but its function is not restricted to this developmental process. In this report, we have examined the possible role of vestigial in the formation of the peripheral nervous system. We found that most vestigial mutants display ectopic or missing macrochaetae. We also show that vestigial interacts in a dose dependant manner with different alleles of the scute gene and with the extramacrochaetae gene and that mis-expression of the vestigial gene in the wing disc increases the domain of scute expression and allows the formation of supernumerary ectopic bristles. From these results, we conclude that vestigial affects scute expression and plays a role in the differentiation of the peripheral nervous system.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
0167-7063
pubmed:author
pubmed:issnType
Print
pubmed:volume
12
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
87-99
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1998
pubmed:articleTitle
The vestigial gene of Drosophila melanogaster is involved in the formation of the peripheral nervous system: genetic interactions with the scute gene.
pubmed:affiliation
Laboratoire de Génétique Quantitative et Moléculaire, Institut Jacques Monod, Paris, France. zider@ijm.jussieu.fr
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't