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rdf:type |
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lifeskim:mentions |
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pubmed:dateCreated |
1977-4-30
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pubmed:abstractText |
The effect of saralasin in lowering blood pressure and plasma aldosterone concentration in normal subjects, both sodium-replete and sodium-deplete, and in patients with various forms of hypertension, is closely related to the basal plasma angiotensin II concentration. These findings confirm and extend earlier studies of angiotensin II/arterial pressure and angiotensin II/aldosterone dose-response curves. They also emphasize the importance of the renin-angiotensin system in the control of aldosterone in sodium depletion and in renal hypertension.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
0079-6085
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
12
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
230-41
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pubmed:dateRevised |
2009-11-11
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pubmed:meshHeading |
pubmed-meshheading:1019166-Aldosterone,
pubmed-meshheading:1019166-Angiotensin II,
pubmed-meshheading:1019166-Blood Pressure,
pubmed-meshheading:1019166-Diet,
pubmed-meshheading:1019166-Humans,
pubmed-meshheading:1019166-Hyperaldosteronism,
pubmed-meshheading:1019166-Hypertension,
pubmed-meshheading:1019166-Kidney Failure, Chronic,
pubmed-meshheading:1019166-Male,
pubmed-meshheading:1019166-Renal Artery Obstruction,
pubmed-meshheading:1019166-Renin,
pubmed-meshheading:1019166-Saralasin,
pubmed-meshheading:1019166-Sodium,
pubmed-meshheading:1019166-Time Factors
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pubmed:year |
1976
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pubmed:articleTitle |
The effects of the angiotensin II antagonist saralasin on blood pressure and plasma aldosterone in man in relation to the prevailing plasma angiotensin II concentration.
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pubmed:publicationType |
Journal Article
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