Linked Life Data

1014039

Source:http://linkedlifedata.com/resource/pubmed/id/1014039

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
1977-3-31
pubmed:abstractText
The metabolism of estradiol-17beta by the guinea pig uterus late in pregnancy was studied in vivo and in vitro. Whole uteri were examined for estrogen metabolites one hour following an intravenous injection of [3H]-estradiol-17beta or uterine sections were examined after incubation for one hour at 37 degrees C in medium containing [3H]-estradiol-17beta. In both instances uterine tissue metabolized estradiol-17beta to five products; estrone, estrone-3-sulfate, 17beta-estradiol-3-sulfate, estrone-3-glucuronide and 17beta-estradiol-3-glucuronide. Of the total radioactive products 11-43% were glucuronides, 17-26% were sulfates and 4-17% was estrone. These results indicate that the guinea pig uterus actively transforms estradiol-17beta into glucuronides and sulfates late in pregnancy.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
0039-128X
pubmed:author
pubmed:issnType
Print
pubmed:volume
28
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
613-9
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1976
pubmed:articleTitle
Metabolites of estradiol-17beta in guinea pig uterus late in pregnancy.
pubmed:publicationType
Journal Article, In Vitro