Linked Life Data

1011381

Source:http://linkedlifedata.com/resource/pubmed/id/1011381

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1977-3-31
pubmed:abstractText
Thin slices, 500 mum in thickness, prepared from the guinea pig olfactory cortex and maintained in vitro, generate presynaptic and postsynaptic potentials following electrical stimulation of the lateral olfactory tract. These responses, however, cannot be elicited immediately after slice preparation; they start to develop gradually as the incubation continues. It was found that there was a remarkable time lag for the development between the pre- and the postsynaptic potentials. The presynaptic potential appeared early and developed its maximum height within 10 to 20 min from the onset of incubation. This time course was only slightly influenced by low temperature. Development of the postsynaptic potential in incubation was delayed and the time required to obtain the maximum height was about 30 min at 37 degrees C and 70 min at 22 degrees C. Upon step-like warming from 24 degrees C to 37 degrees C, there was a rapid increase in the amplitude of the response. In the glucose-deficient solution the presynaptic potential maintained its amplitude longer than the postsynaptic potential. Frequency potentiation of the postsynaptic potential was studied by applying a train of six stimuli. The maximum augmented ratio among six responses was the highest in early incubation and reached a steady at 50 min. The ratio of the post-tetanic potentiation of olfactory neurons was the highest at 5 min incubation and reached a steady at 20 min.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0021-521X
pubmed:author
pubmed:issnType
Print
pubmed:volume
26
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
355-65
pubmed:dateRevised
2008-11-21
pubmed:meshHeading
pubmed:year
1976
pubmed:articleTitle
Temperature influence on the development of electrical activities in mammalian brain slice during incubation.
pubmed:publicationType
Journal Article