Source:http://linkedlifedata.com/resource/pubmed/id/10103145
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
1999-4-16
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pubmed:abstractText |
The immune system of the patients with colorectal cancer is activated. Urinary neopterin is an index of this systemic immune activation, reflecting the circulating activity of interferon-gamma. We have measured urinary neopterin excretion in 34 patients with colorectal cancer. This excretion was significantly higher in our patients compared to reference group (325 +/- 267 vs 169 +/- 62 mumol/mol creatinine, neopterin concentrations were considerably higher in Dukes' stage D disease compared with Dukes' stage B and C disease/561 +/- 372 vs 188 +/- 47 and 250 +/- 142 mu/mol creatinine. Increased neopterin detected the presence of metastatic disease with 90% sensitivity and 87.5% specificity. Authors conclude that urinary neopterin measurement may be useful in the staging of colorectal cancer.
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pubmed:language |
cze
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
1211-247X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
40
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
81-2
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:10103145-Colorectal Neoplasms,
pubmed-meshheading:10103145-Creatinine,
pubmed-meshheading:10103145-Female,
pubmed-meshheading:10103145-Humans,
pubmed-meshheading:10103145-Male,
pubmed-meshheading:10103145-Middle Aged,
pubmed-meshheading:10103145-Neoplasm Staging,
pubmed-meshheading:10103145-Neopterin,
pubmed-meshheading:10103145-Sensitivity and Specificity,
pubmed-meshheading:10103145-Tumor Markers, Biological
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pubmed:year |
1997
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pubmed:articleTitle |
[Activation of the immune system in colorectal carcinoma and its assessment].
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pubmed:affiliation |
Chirurgická klinika LF UK a FN v Hradci Králové.
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pubmed:publicationType |
Journal Article,
English Abstract
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