Linked Life Data

10084848

Source:http://linkedlifedata.com/resource/pubmed/id/10084848

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1999-3-17
pubmed:abstractText
Impaired coronary reserve (CR) with angiographic coronary arteries has been demonstrated in patients with left ventricular hypertrophy (LVH) in response to valvular heart disease or hypertension. To determine if adaptive LVH induced by intensive training may alter myocardial blood flow (MBF) and CR, 8 highly trained endurance tri- athletes (29.6 +/- 4.0 yrs, with echographic LVH) were compared with 6 control subjects (33.0 +/- 7.9 yrs, with a normal echographic examination). Triathletes entered the study if they had a left ventricular mass >120 g/m2 at 2-D echocardiographic measurements (mean = 148.6 +/- 19.8 g/m2). MBF was assessed using positron emission tomography (PET) with H2O15. Subjects underwent an intravenous bolus of 17- 25 mCi of H2)15 at baseline and after intravenous infusion of 0.80 mg/kg of dipyridimole; H2O15 examination was followed by an F18-fluorodeoxyglucose (FDG) myocardial imaging. CR was determined as the ration of maximal to basal myocardial blood flow. In comparison with controls, triathletes with LVH showed normal MBF values (0.74 +/- 0.1 vs 0.8 +/- 0.2 ml/ml/min, p = 0.2), but an increased CR (3.8 +/- 0.7 vs 6.1 +/-1.9, p < 0.05). In contrast with other forms of LVH, CR is not altered in LVH due intense physical training. These results suggest that LVH due to intensive physical training is associated with an increase in coronary blood flow capacity.
pubmed:language
fre
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
1066-7814
pubmed:author
pubmed:issnType
Print
pubmed:volume
24
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
87-95
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1999
pubmed:articleTitle
[Cardiac hypertrophy and coronary reserve in endurance athletes].
pubmed:affiliation
ADDMS 94, Centre Département de Médecine du Sport, Créteil, France.
pubmed:publicationType
Journal Article, English Abstract