Linked Life Data

10076875

Source:http://linkedlifedata.com/resource/pubmed/id/10076875

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1999-5-6
pubmed:abstractText
Neurosecretory granules are conveyed along microtubules in the neurohypophysial axon. By both quick-freeze deep-etch and thin section electron microscopies, we found cross-bridges between the granules and microtubules. The length of the cross-bridges (mean 26.6 +/- 15.2 nm) was not uniform, and its histogram was multi-phasic showing the highest peak around 20 nm and several lower peaks in the range of 40-100 nm. This implies that cross-bridges are complexes of several kinds of constituents. Immunofluorescence microscopy showed the expression of a motor protein kinesin in the mouse neurohypophysis. Immunoelectron microscopy detected kinesin at the contact sites of neurosecretory granules to microtubules. These results suggest that kinesin is a major component of the cross-bridges, and involved in the neurosecretory granule transportation.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
0304-3940
pubmed:author
pubmed:issnType
Print
pubmed:day
26
pubmed:volume
262
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
69-71
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1999
pubmed:articleTitle
Kinesin cross-bridges between neurosecretory granules and microtubules in the mouse neurohypophysis.
pubmed:affiliation
Department of Anatomy I, Nagoya University School of Medicine, Japan. senda@tsuru.med.nagoya-u.ac.jp
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't