Source:http://linkedlifedata.com/resource/pubmed/id/10025761
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2 Pt 1
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pubmed:dateCreated |
1999-3-5
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pubmed:abstractText |
Nasal and nasal-type natural killer (NK)/T-cell lymphomas follow an aggressive course and have a poor prognosis. Recent pathologic studies suggest that the disease is a malignant proliferation of NK cells, which often express CD56. An association with the Epstein-Barr virus has also been reported. Skin involvement occurred in each of the 3 patients studied. Radiation therapy provided some benefit to the patients in the early stages. Conventional chemotherapies were not effective. To overcome this multiple-drug resistance of the tumor cells, cyclosporine and high-dose chemotherapy was combined with peripheral-blood stem-cell transplantation. The average life span from the onset of the disease for our patients was 9.6 months. Further improvement in the management of nasal and nasal-type NK/T-cell lymphomas is necessary.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0190-9622
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
40
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
268-72
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:10025761-Adult,
pubmed-meshheading:10025761-Aged,
pubmed-meshheading:10025761-Fatal Outcome,
pubmed-meshheading:10025761-Female,
pubmed-meshheading:10025761-Humans,
pubmed-meshheading:10025761-Immunohistochemistry,
pubmed-meshheading:10025761-Killer Cells, Natural,
pubmed-meshheading:10025761-Lymphoma, T-Cell, Cutaneous,
pubmed-meshheading:10025761-Male,
pubmed-meshheading:10025761-Nose Neoplasms,
pubmed-meshheading:10025761-Skin Neoplasms
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pubmed:year |
1999
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pubmed:articleTitle |
Nasal and nasal-type natural killer/T-cell lymphoma.
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pubmed:affiliation |
Department of Dermatology, Okayama University Medical School, Japan.
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pubmed:publicationType |
Journal Article,
Case Reports
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