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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
|
pubmed:dateCreated |
1977-2-24
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pubmed:abstractText |
The kinetics of active K+ transport were studied in immature red blood cells cells from high-K+ and low-K+ sheep particulary with respect to the effects of varying intracellular K+ concentration, [K]i. Comparison was made with active transport, or pump, activity in mature high-K+ and low-K+ red cells. Reticulocytes from both types of sheep had much higher maximal active K+ influxes than did mature cells. In both types of reticulocytes, and in mature high-K+ cells as well, the pump was relatively insensitive to increasing [K]i. In contrast, intracellular K+ markedly inhibited the pump in mature low-K+ cells. Active K+ transport in low-K+ reticulocytes, however, as in mature low-K+ cells, is stimulated by specific isoimmune anti-L serum. Therefore the K+ pumps of high-K+ and low-K+ reticulocytes have similar kinetic properties. Maturation of the red cells, involving inactivation of most of the pump activity in both cell types, results in mature high-K+ and low-K+ cells with K+ pumps of very different kinetic characteristics.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
0006-3002
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
14
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pubmed:volume |
455
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pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
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pubmed:pagination |
749-58
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:999938-Anemia,
pubmed-meshheading:999938-Animals,
pubmed-meshheading:999938-Biological Transport, Active,
pubmed-meshheading:999938-Erythropoiesis,
pubmed-meshheading:999938-Kinetics,
pubmed-meshheading:999938-Potassium,
pubmed-meshheading:999938-Reticulocytes,
pubmed-meshheading:999938-Sheep
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pubmed:year |
1976
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pubmed:articleTitle |
Active potassium transport in reticulocytes of high-K+ and low-K+ sheep.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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