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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
1999-4-13
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pubmed:abstractText |
A series of 6/7-mono and disubstituted quinolone-3-carboxamide derivatives (1-12) were synthesized and their in vitro methemoglobin producing capacity have been delineated. The compounds 5, 6, 9 and 10 showed minimum methemoglobin toxicity.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0960-894X
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
4
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pubmed:volume |
9
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
25-30
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:9990450-Amides,
pubmed-meshheading:9990450-Animals,
pubmed-meshheading:9990450-Anti-Infective Agents,
pubmed-meshheading:9990450-Ciprofloxacin,
pubmed-meshheading:9990450-Cytochrome-B(5) Reductase,
pubmed-meshheading:9990450-Dogs,
pubmed-meshheading:9990450-Dose-Response Relationship, Drug,
pubmed-meshheading:9990450-Drug Evaluation, Preclinical,
pubmed-meshheading:9990450-Methemoglobin,
pubmed-meshheading:9990450-Methemoglobinemia,
pubmed-meshheading:9990450-Norfloxacin,
pubmed-meshheading:9990450-Ofloxacin,
pubmed-meshheading:9990450-Quinolones,
pubmed-meshheading:9990450-Structure-Activity Relationship
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pubmed:year |
1999
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pubmed:articleTitle |
Synthesis and methemoglobin toxicity of the amides of 6/7 mono or disubstituted quinolone.
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pubmed:affiliation |
Division of Biochemistry, Central Drug Research Institute, Lucknow, India.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
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