Linked Life Data

9988450

Source:http://linkedlifedata.com/resource/pubmed/id/9988450

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
1999-4-23
pubmed:abstractText
There is now a reasonable body of data that would suggest that the immunopathology of asthma is similar, if not identical, in childhood asthmatics compared with adult asthmatics. Indeed, we now have evidence that much of the immunopathology is established within the airways of asthmatics very early after the onset of symptoms and, given the lack of correlation with duration of symptoms, may even antedate the first manifestations. There are, however, some differences with neutrophil recruitment being somewhat more prominent than has been recorded from adult observations. The utility of any inflammation parameter in identifying the real future asthmatics has yet to be studied in sufficient detail to define sensitivity, specificity and predictive value. Such studies will be an essential prerequisite to establishing very early intervention strategies, particularly if these involve the use of inhaled and/or oral corticosteroid.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
0954-7894
pubmed:author
pubmed:issnType
Print
pubmed:volume
28 Suppl 5
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
71-5; discussion 90-1
pubmed:dateRevised
2005-11-16
pubmed:meshHeading
pubmed:year
1998
pubmed:articleTitle
Inflammatory mechanisms in childhood asthma.
pubmed:affiliation
Department of Child Health, University of Southampton/Southampton General Hospital, UK.
pubmed:publicationType
Journal Article, Review