Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1999-3-16
pubmed:abstractText
Multilocus enzyme electrophoresis (MLEE) of 397 Vibrio cholerae isolates, including 143 serogroup reference strains and 244 strains from Mexico and Guatemala, identified 279 electrophoretic types (ETs) distributed in two major divisions (I and II). Linkage disequilibrium was demonstrated in both divisions and in subdivision Ic of division I but not in subdivision Ia, which includes 76% of the ETs. Despite this evidence of relatively frequent recombination, clonal lineages may persist for periods of time measured in at least decades. In addition to the pandemic clones of serogroups O1 and O139, which form a tight cluster of four ETs in subdivision Ia, MLEE analysis identified numerous apparent clonal lineages of non-O1 strains with intercontinental distributions. A clone of serogroup O37 that demonstrated epidemic potential in the 1960s is closely related to the pandemic O1/O139 clones, but the nontoxigenic O1 Inaba El Tor reference strain is not. A strain of serogroup O22, which has been identified as the most likely donor of exogenous rfb region DNA to the O1 progenitor of the O139 clone, is distantly related to the O1/O139 clones. The close evolutionary relationships of the O1, O139, and O37 epidemic clones indicates that new cholera clones are likely to arise by the modification of a lineage that is already epidemic or is closely related to such a clone.
pubmed:grant
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/9986816-1400239, http://linkedlifedata.com/resource/pubmed/commentcorrection/9986816-1755069, http://linkedlifedata.com/resource/pubmed/commentcorrection/9986816-1774258, http://linkedlifedata.com/resource/pubmed/commentcorrection/9986816-1862091, http://linkedlifedata.com/resource/pubmed/commentcorrection/9986816-1879486, http://linkedlifedata.com/resource/pubmed/commentcorrection/9986816-2425735, http://linkedlifedata.com/resource/pubmed/commentcorrection/9986816-3053773, http://linkedlifedata.com/resource/pubmed/commentcorrection/9986816-3256999, http://linkedlifedata.com/resource/pubmed/commentcorrection/9986816-4564589, http://linkedlifedata.com/resource/pubmed/commentcorrection/9986816-6340107, http://linkedlifedata.com/resource/pubmed/commentcorrection/9986816-7002028, http://linkedlifedata.com/resource/pubmed/commentcorrection/9986816-7479787, http://linkedlifedata.com/resource/pubmed/commentcorrection/9986816-7528734, http://linkedlifedata.com/resource/pubmed/commentcorrection/9986816-7557467, http://linkedlifedata.com/resource/pubmed/commentcorrection/9986816-7678018, http://linkedlifedata.com/resource/pubmed/commentcorrection/9986816-7680060, http://linkedlifedata.com/resource/pubmed/commentcorrection/9986816-7704895, http://linkedlifedata.com/resource/pubmed/commentcorrection/9986816-7768818, http://linkedlifedata.com/resource/pubmed/commentcorrection/9986816-7797907, http://linkedlifedata.com/resource/pubmed/commentcorrection/9986816-7835331, http://linkedlifedata.com/resource/pubmed/commentcorrection/9986816-7928989, http://linkedlifedata.com/resource/pubmed/commentcorrection/9986816-7937867, http://linkedlifedata.com/resource/pubmed/commentcorrection/9986816-7972070, http://linkedlifedata.com/resource/pubmed/commentcorrection/9986816-8095620, http://linkedlifedata.com/resource/pubmed/commentcorrection/9986816-8095621, http://linkedlifedata.com/resource/pubmed/commentcorrection/9986816-8101921, http://linkedlifedata.com/resource/pubmed/commentcorrection/9986816-8108402, http://linkedlifedata.com/resource/pubmed/commentcorrection/9986816-8146152, http://linkedlifedata.com/resource/pubmed/commentcorrection/9986816-8506277, http://linkedlifedata.com/resource/pubmed/commentcorrection/9986816-8566700, http://linkedlifedata.com/resource/pubmed/commentcorrection/9986816-8590409, http://linkedlifedata.com/resource/pubmed/commentcorrection/9986816-8658163, http://linkedlifedata.com/resource/pubmed/commentcorrection/9986816-8735097, http://linkedlifedata.com/resource/pubmed/commentcorrection/9986816-8760931, http://linkedlifedata.com/resource/pubmed/commentcorrection/9986816-8953025, http://linkedlifedata.com/resource/pubmed/commentcorrection/9986816-9034311, http://linkedlifedata.com/resource/pubmed/commentcorrection/9986816-9098074, http://linkedlifedata.com/resource/pubmed/commentcorrection/9986816-9348159, http://linkedlifedata.com/resource/pubmed/commentcorrection/9986816-9352899, http://linkedlifedata.com/resource/pubmed/commentcorrection/9986816-9394556, http://linkedlifedata.com/resource/pubmed/commentcorrection/9986816-9501228, http://linkedlifedata.com/resource/pubmed/commentcorrection/9986816-9508329, http://linkedlifedata.com/resource/pubmed/commentcorrection/9986816-9675855
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
0095-1137
pubmed:author
pubmed:issnType
Print
pubmed:volume
37
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
581-90
pubmed:dateRevised
2009-11-18
pubmed:meshHeading
pubmed:year
1999
pubmed:articleTitle
Genetic diversity and population structure of Vibrio cholerae.
pubmed:affiliation
Departamento de Salud Pública de la Facultad de Medicina, Universidad Nacional Autónoma de México, México, D.F., México.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, Non-U.S. Gov't