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pubmed-article:9934483pubmed:abstractTextdelta 7-5-Desaturase catalyses one of the last steps in ergosterol biosynthesis in fungi. Moreover delta 5-unsaturation is necessary for the sparking function. Synthesis of three pairs of C-6 epimeric cholestanol derivatives are described as potential growth inhibitors. Preliminary results suggest that 6 beta-aminocholestanol is a potent antifungal agent.lld:pubmed
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pubmed-article:9934483pubmed:articleTitleSynthesis of 6(alpha, beta)-aminocholestanols as ergosterol biosynthesis inhibitors.lld:pubmed
pubmed-article:9934483pubmed:affiliationLaboratoire de Synthèse et Etude de Substances Naturelles à Activités Biologiques, Université de La Rochelle, France.lld:pubmed
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