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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
24
|
| pubmed:dateCreated |
1999-4-5
|
| pubmed:abstractText |
delta 7-5-Desaturase catalyses one of the last steps in ergosterol biosynthesis in fungi. Moreover delta 5-unsaturation is necessary for the sparking function. Synthesis of three pairs of C-6 epimeric cholestanol derivatives are described as potential growth inhibitors. Preliminary results suggest that 6 beta-aminocholestanol is a potent antifungal agent.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Dec
|
| pubmed:issn |
0960-894X
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:day |
15
|
| pubmed:volume |
8
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
3627-30
|
| pubmed:dateRevised |
2006-11-15
|
| pubmed:meshHeading |
pubmed-meshheading:9934483-Antifungal Agents,
pubmed-meshheading:9934483-Candida albicans,
pubmed-meshheading:9934483-Cholestanols,
pubmed-meshheading:9934483-Ergosterol,
pubmed-meshheading:9934483-Magnetic Resonance Spectroscopy,
pubmed-meshheading:9934483-Molecular Structure,
pubmed-meshheading:9934483-Saccharomyces cerevisiae
|
| pubmed:year |
1998
|
| pubmed:articleTitle |
Synthesis of 6(alpha, beta)-aminocholestanols as ergosterol biosynthesis inhibitors.
|
| pubmed:affiliation |
Laboratoire de Synthèse et Etude de Substances Naturelles à Activités Biologiques, Université de La Rochelle, France.
|
| pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|