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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
24
|
pubmed:dateCreated |
1999-4-5
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pubmed:abstractText |
The synthesis and activity of a series of 4,5-diarylimidazole analogs are described. One analog had an IC50 of 80 nM, was 6750-selective against COX-1, and demonstrated in vivo potency in the mouse air pouch model.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Dec
|
pubmed:issn |
0960-894X
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:day |
15
|
pubmed:volume |
8
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
3443-8
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pubmed:dateRevised |
2003-11-14
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pubmed:meshHeading | |
pubmed:year |
1998
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pubmed:articleTitle |
Antiinflammatory 4,5-diarylimidazoles as selective cyclooxygenase inhibitors.
|
pubmed:affiliation |
G.D. Searle and Co., Skokie, IL 60077, USA.
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pubmed:publicationType |
Journal Article
|