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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
1999-3-1
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pubmed:abstractText |
A disordered proliferative process in the vascular wall is thought to underlie the pathogenesis of restenosis after percutaneous transluminal angioplasty and carotid endarterectomy. A growth inhibitory property of overexpressed prostacyclin (PGI2) synthase (PGIS) was recently implicated in the pathological proliferation of vascular smooth muscle cells (VSMC) in vitro. Here, we investigated the effects of increased PGI2 synthesis on the pathological proliferation of VSMCs.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0039-2499
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pubmed:author |
pubmed-author:AokiMM,
pubmed-author:HaraSS,
pubmed-author:HashimotoNN,
pubmed-author:HataeTT,
pubmed-author:KanedaYY,
pubmed-author:MorishitaRR,
pubmed-author:NagataII,
pubmed-author:OgiharaTT,
pubmed-author:TanabeTT,
pubmed-author:TodakaTT,
pubmed-author:TsukaharaTT,
pubmed-author:YanamotoHH,
pubmed-author:YokoyamaCC
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pubmed:issnType |
Print
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pubmed:volume |
30
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
419-26
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pubmed:dateRevised |
2010-11-18
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pubmed:meshHeading |
pubmed-meshheading:9933282-6-Ketoprostaglandin F1 alpha,
pubmed-meshheading:9933282-Animals,
pubmed-meshheading:9933282-Antibodies,
pubmed-meshheading:9933282-Balloon Dilation,
pubmed-meshheading:9933282-Carotid Artery, Common,
pubmed-meshheading:9933282-Carotid Artery Injuries,
pubmed-meshheading:9933282-Carotid Stenosis,
pubmed-meshheading:9933282-Cell Division,
pubmed-meshheading:9933282-Cytochrome P-450 Enzyme System,
pubmed-meshheading:9933282-Endothelium, Vascular,
pubmed-meshheading:9933282-Epoprostenol,
pubmed-meshheading:9933282-Follow-Up Studies,
pubmed-meshheading:9933282-Gene Transfer Techniques,
pubmed-meshheading:9933282-Genetic Vectors,
pubmed-meshheading:9933282-Humans,
pubmed-meshheading:9933282-Immunoblotting,
pubmed-meshheading:9933282-Intramolecular Oxidoreductases,
pubmed-meshheading:9933282-Liposomes,
pubmed-meshheading:9933282-Male,
pubmed-meshheading:9933282-Muscle, Smooth, Vascular,
pubmed-meshheading:9933282-Rabbits,
pubmed-meshheading:9933282-Rats,
pubmed-meshheading:9933282-Rats, Sprague-Dawley,
pubmed-meshheading:9933282-Respirovirus,
pubmed-meshheading:9933282-Tunica Intima
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pubmed:year |
1999
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pubmed:articleTitle |
Gene transfer of human prostacyclin synthase prevents neointimal formation after carotid balloon injury in rats.
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pubmed:affiliation |
Department of Cerebrovascular Surgery, Laboratory for Cerebrovascular Disorders, National Cardio-Vascular Center, Osaka University Medical Center, Osaka, Japan.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
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