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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1 Suppl 1
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pubmed:dateCreated |
1999-4-13
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pubmed:abstractText |
Pharmacologic modulation of the contents of the pericardial space has been shown to influence the response of coronary arteries to balloon injury. Endoluminal (EL) local delivery of various drugs into coronaries has been found to be limited by short residence time, as well as by highly variable deposited agent concentration. We hypothesized that compounds placed into the pericardial space (P) would penetrate into coronary tissue with greater consistency than seen after EL delivery and provide for prolonged coronary exposure to agents.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0160-9289
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
22
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
I10-6
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pubmed:dateRevised |
2010-11-18
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pubmed:meshHeading |
pubmed-meshheading:9929762-Albumins,
pubmed-meshheading:9929762-Animals,
pubmed-meshheading:9929762-Autoradiography,
pubmed-meshheading:9929762-Balloon Dilation,
pubmed-meshheading:9929762-Coronary Vessels,
pubmed-meshheading:9929762-Fibroblast Growth Factor 2,
pubmed-meshheading:9929762-Image Processing, Computer-Assisted,
pubmed-meshheading:9929762-Injections,
pubmed-meshheading:9929762-Injections, Intra-Arterial,
pubmed-meshheading:9929762-Iodine Radioisotopes,
pubmed-meshheading:9929762-Myocardium,
pubmed-meshheading:9929762-Pericardium,
pubmed-meshheading:9929762-Platelet-Derived Growth Factor,
pubmed-meshheading:9929762-Radiopharmaceuticals,
pubmed-meshheading:9929762-Reproducibility of Results,
pubmed-meshheading:9929762-Serum Albumin, Radio-Iodinated,
pubmed-meshheading:9929762-Swine,
pubmed-meshheading:9929762-Time Factors,
pubmed-meshheading:9929762-Tissue Distribution
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pubmed:year |
1999
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pubmed:articleTitle |
Pharmacokinetics and consistency of pericardial delivery directed to coronary arteries: direct comparison with endoluminal delivery.
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pubmed:affiliation |
Krannert Institute of Cardiology, Indiana University School of Medicine, Indianapolis, USA.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
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