| pubmed-article:9927997 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:9927997 | lifeskim:mentions | umls-concept:C0086418 | lld:lifeskim |
| pubmed-article:9927997 | lifeskim:mentions | umls-concept:C0009015 | lld:lifeskim |
| pubmed-article:9927997 | lifeskim:mentions | umls-concept:C0084056 | lld:lifeskim |
| pubmed-article:9927997 | lifeskim:mentions | umls-concept:C0205245 | lld:lifeskim |
| pubmed-article:9927997 | lifeskim:mentions | umls-concept:C0086860 | lld:lifeskim |
| pubmed-article:9927997 | lifeskim:mentions | umls-concept:C1825477 | lld:lifeskim |
| pubmed-article:9927997 | lifeskim:mentions | umls-concept:C1880022 | lld:lifeskim |
| pubmed-article:9927997 | pubmed:dateCreated | 1999-2-16 | lld:pubmed |
| pubmed-article:9927997 | pubmed:abstractText | The 5'-flanking region (1.5 kb) of the gene coding for the human VIP1/PACAP receptor was isolated, sequenced, and characterized. Transient expression of constructs containing sequentially deleted 5'-flanking sequences of the VIP1/PACAP receptor fused to a luciferase reporter gene showed that this sequence was active as a promoter in the intestinal cancer cell line, HT-29, expressing endogenous VIP1/PACAP receptor. The shortest DNA fragment with significant promoter activity encompassed the region from -205 to +76 bp. Deletion of a CCAAT-box sequence in the construction corresponding to -173 to +76 bp dramatically reduced the promoter activity. The promoter -205 to +76 bp has a housekeeping gene structure without TATA-box. It contains GC-rich regions characterized by potential Sp1 and AP2 sites and some potential regulatory elements, such as CRE and ATF, and a CCAAT-box sequence (-182 to -178) crucial for gene transcription. | lld:pubmed |
| pubmed-article:9927997 | pubmed:language | eng | lld:pubmed |
| pubmed-article:9927997 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9927997 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:9927997 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9927997 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9927997 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9927997 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
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| pubmed-article:9927997 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9927997 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:9927997 | pubmed:month | Dec | lld:pubmed |
| pubmed-article:9927997 | pubmed:issn | 0077-8923 | lld:pubmed |
| pubmed-article:9927997 | pubmed:author | pubmed-author:LaburtheMM | lld:pubmed |
| pubmed-article:9927997 | pubmed:author | pubmed-author:MaoretJ JJJ | lld:pubmed |
| pubmed-article:9927997 | pubmed:author | pubmed-author:CouvineauAA | lld:pubmed |
| pubmed-article:9927997 | pubmed:author | pubmed-author:Rouyer-Fessar... | lld:pubmed |
| pubmed-article:9927997 | pubmed:author | pubmed-author:CarreroII | lld:pubmed |
| pubmed-article:9927997 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:9927997 | pubmed:day | 11 | lld:pubmed |
| pubmed-article:9927997 | pubmed:volume | 865 | lld:pubmed |
| pubmed-article:9927997 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:9927997 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:9927997 | pubmed:pagination | 59-63 | lld:pubmed |
| pubmed-article:9927997 | pubmed:dateRevised | 2008-11-21 | lld:pubmed |
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| pubmed-article:9927997 | pubmed:meshHeading | pubmed-meshheading:9927997-... | lld:pubmed |
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| pubmed-article:9927997 | pubmed:meshHeading | pubmed-meshheading:9927997-... | lld:pubmed |
| pubmed-article:9927997 | pubmed:year | 1998 | lld:pubmed |
| pubmed-article:9927997 | pubmed:articleTitle | Cloning and functional characterization of the human VIP1/PACAP receptor promoter. | lld:pubmed |
| pubmed-article:9927997 | pubmed:affiliation | Laboratoire de Neuroendocrinologie et Biologie Cellulaire Digestives, Institut National de la Santé et de la Recherche Médicale, INSERM U-410, Faculté de Médecine Xavier Bichat, Paris, France. coucou@bichat.inserm.fr | lld:pubmed |
| pubmed-article:9927997 | pubmed:publicationType | Journal Article | lld:pubmed |
| entrez-gene:7433 | entrezgene:pubmed | pubmed-article:9927997 | lld:entrezgene |
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| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9927997 | lld:pubmed |
