rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
1999-2-25
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pubmed:abstractText |
Keratinocyte growth factor-2 (KGF-2) also described as fibroblast growth factor-10 (FGF-10) is a newly identified member of the fibroblast growth factor family. KGF-2 is 96% identical to the recently identified rat FGF-10 and specifically stimulates growth of normal human epidermal keratinocytes. The present study was undertaken to examine the effects of topically applied KGF-2 in an incisional wound healing model. KGF-2 treatment resulted in an improvement in incisional wound healing as characterized by an increase in breaking strength, collagen content, and epidermal thickness.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/FGF10 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/FGF7 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Fgf10 protein, rat,
http://linkedlifedata.com/resource/pubmed/chemical/Fgf7 protein, rat,
http://linkedlifedata.com/resource/pubmed/chemical/Fibroblast Growth Factor 10,
http://linkedlifedata.com/resource/pubmed/chemical/Fibroblast Growth Factor 7,
http://linkedlifedata.com/resource/pubmed/chemical/Fibroblast Growth Factors,
http://linkedlifedata.com/resource/pubmed/chemical/Growth Substances,
http://linkedlifedata.com/resource/pubmed/chemical/Recombinant Proteins
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0022-4804
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pubmed:author |
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pubmed:copyrightInfo |
Copyright 1999 Academic Press.
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pubmed:issnType |
Print
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pubmed:volume |
81
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
238-42
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:9927546-Animals,
pubmed-meshheading:9927546-Fibroblast Growth Factor 10,
pubmed-meshheading:9927546-Fibroblast Growth Factor 7,
pubmed-meshheading:9927546-Fibroblast Growth Factors,
pubmed-meshheading:9927546-Growth Substances,
pubmed-meshheading:9927546-Humans,
pubmed-meshheading:9927546-Keratinocytes,
pubmed-meshheading:9927546-Male,
pubmed-meshheading:9927546-Rats,
pubmed-meshheading:9927546-Rats, Sprague-Dawley,
pubmed-meshheading:9927546-Recombinant Proteins,
pubmed-meshheading:9927546-Skin,
pubmed-meshheading:9927546-Skin Physiological Phenomena,
pubmed-meshheading:9927546-Tensile Strength,
pubmed-meshheading:9927546-Wound Healing
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pubmed:year |
1999
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pubmed:articleTitle |
Keratinocyte growth factor-2 accelerates wound healing in incisional wounds.
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pubmed:affiliation |
Human Genome Sciences, Inc., Rockville, Maryland, 20850, USA. jimenez@hgsi.com
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pubmed:publicationType |
Journal Article
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