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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:dateCreated |
1999-3-15
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pubmed:abstractText |
Aside from HLA identical sibling donors, spousal donor transplants are the best living donors because their 3-year graft survival is comparable to that of all other living donors--with the exception of HLA identical siblings. Interestingly, the 14.5 year half-life of spousal donor kidneys was superior to the 10.8 year half-life of other living donor transplants. Better quality kidneys is the principal explanation for higher spousal donor graft survival rates when compared with cadaver donors. This was evident from the 2% anuria rate in the first post-operative day for spouse donor compared with 10% of cadaver donor transplants. Moreover, the requirement for dialysis was 6% for spouse donor grafts compared with 22% of cadaver donor transplants. The damage is not attributable to cold ischemia time but rather to agonal events and shock prior to kidney harvesting. In a survey of 176 spousal renal transplant donors, 175 of 176 said they would advise others to donate a kidney to a spouse--and only one donor advised against it. Of the "yes" responses, 28% provided additional comments enthusiastically recommending it. About 47% reported improvements in the marital relationship, 29% in the sexual relationship, and 25% described improved relations with their children. The fact that the donor reaps many direct personal benefits should make spousal donation the first consideration for living-donation (after the HLA-identical sibling donor).
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:issn |
0890-9016
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
269-84
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:9919411-Adolescent,
pubmed-meshheading:9919411-Adult,
pubmed-meshheading:9919411-Cadaver,
pubmed-meshheading:9919411-Child,
pubmed-meshheading:9919411-Child, Preschool,
pubmed-meshheading:9919411-Female,
pubmed-meshheading:9919411-Graft Survival,
pubmed-meshheading:9919411-Histocompatibility Testing,
pubmed-meshheading:9919411-Humans,
pubmed-meshheading:9919411-Infant,
pubmed-meshheading:9919411-Kidney Transplantation,
pubmed-meshheading:9919411-Living Donors,
pubmed-meshheading:9919411-Male,
pubmed-meshheading:9919411-Middle Aged,
pubmed-meshheading:9919411-Nuclear Family,
pubmed-meshheading:9919411-Pregnancy,
pubmed-meshheading:9919411-Registries,
pubmed-meshheading:9919411-Spouses,
pubmed-meshheading:9919411-Tissue Donors,
pubmed-meshheading:9919411-Tissue and Organ Procurement,
pubmed-meshheading:9919411-United States
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pubmed:year |
1997
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pubmed:articleTitle |
Spousal and other living renal donor transplants.
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pubmed:publicationType |
Journal Article
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