|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
7
|
|
pubmed:dateCreated |
1977-1-25
|
|
pubmed:abstractText |
Trinitrophenylated Moloney virus-induced YAC cells induced a higher cytotoxic antibody response and better protection against small tumor cell doses in syngeneic, low-responsive strain A mice than nonmodified YAC cells that had been inactivated by irradiation or mitomycin C treatment. The results indicated that genetically determined low responsiveness to a virally induced antigen can be overcome, at least to some extent, by coupling the immunizing cells to a strong immunogenic hapten.
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Jul
|
|
pubmed:issn |
0014-2980
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
6
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
473-6
|
|
pubmed:dateRevised |
2006-11-15
|
|
pubmed:meshHeading |
pubmed-meshheading:991914-Animals,
pubmed-meshheading:991914-Antibody Formation,
pubmed-meshheading:991914-Antigens, Neoplasm,
pubmed-meshheading:991914-Genes,
pubmed-meshheading:991914-Haptens,
pubmed-meshheading:991914-Lymphocytes,
pubmed-meshheading:991914-Lymphoma,
pubmed-meshheading:991914-Mice,
pubmed-meshheading:991914-Mice, Inbred Strains,
pubmed-meshheading:991914-Moloney murine leukemia virus,
pubmed-meshheading:991914-Neoplasms, Experimental,
pubmed-meshheading:991914-Nitrobenzenes,
pubmed-meshheading:991914-Trinitrobenzenes
|
|
pubmed:year |
1976
|
|
pubmed:articleTitle |
Induction of immune responsiveness in a genetically low-responsive tumor-host combination by chemical modification of the immunogen.
|
|
pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
|
