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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
1
|
| pubmed:dateCreated |
1999-4-27
|
| pubmed:abstractText |
Survival from serious burns in children has improved substantially in recent years. Mortality is predominantly determined by the total body surface area burned and the often unrecognised inhalation injury. A retrospective review of 4,451 consecutive children with thermal injuries over a 10-year period was undertaken to determine the incidence, clinical presentation, and pathology of inhalation injury and its contribution to morbidity and mortality. Inhalation burns were diagnosed clinically and confirmed endoscopically and post-mortem in 97 (2.2%) children; 77 sustained fire burns (mean age 4 years) and 20 hot-water burns (mean age 18 months). The Moylan classification stratified them into upper-airway burns in 59 children, major-airway burns in 29, and parenchymal burns in 44. Major-airway burns were always seen in conjunction with either upper-airway or parenchymal injury. Stridor and acute progressive respiratory distress were the two main symptoms, the onset of which was occasionally delayed for up to 72 h. Endoscopy was most helpful in confirming the diagnosis and determining airway management. Endotracheal intubation was needed in more than 50% of children, usually for less than 5 days, and was converted to tracheostomy in only 6. Persistent laryngeal and tracheal damage was identified in 4. Secondary pneumonia occurred in 41.5% of children with fire burns and 55% with hot-water burns. Extensive surface burns, parenchymal injury, and secondary pneumonia all contributed to the significant mortality. Post-mortem findings corroborated clinical and endoscopic evidence. This study suggests that inhalation burns were often not recognised, could present late, and usually had significant consequences. Early clinical diagnosis, supported by endoscopic findings and appropriate management, is essential if the high morbidity and mortality amongst these children is to be improved.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:status |
MEDLINE
|
| pubmed:issn |
0179-0358
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
15
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
50-5
|
| pubmed:dateRevised |
2004-11-17
|
| pubmed:meshHeading |
pubmed-meshheading:9914356-Burns, Inhalation,
pubmed-meshheading:9914356-Cause of Death,
pubmed-meshheading:9914356-Child,
pubmed-meshheading:9914356-Child, Preschool,
pubmed-meshheading:9914356-Female,
pubmed-meshheading:9914356-Humans,
pubmed-meshheading:9914356-Incidence,
pubmed-meshheading:9914356-Infant,
pubmed-meshheading:9914356-Infant, Newborn,
pubmed-meshheading:9914356-Male,
pubmed-meshheading:9914356-Retrospective Studies,
pubmed-meshheading:9914356-South Africa
|
| pubmed:year |
1999
|
| pubmed:articleTitle |
Inhalation burns in children.
|
| pubmed:affiliation |
Department of Paediatric Surgery, Red Cross Children's Hospital, University of Cape Town, Klipfontein Road, Rondebosch, 7700, South Africa.
|
| pubmed:publicationType |
Journal Article
|