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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2-3 SPEC NO
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pubmed:dateCreated |
1977-1-25
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pubmed:abstractText |
Long-chain 1,2-alkanediols can be separated into their enantiomers by thin-layer chromatography of the bis-L-acetylmandelates. The method is also applicable to the separation of enantiomeric 1,3-alkanediols. Both 2-hydroxy fatty acids and 1,2-alkanediols derived from diester waxes of rat skin have the D-configuration. The D-enantiomer of 2DL-1,2-octadecanediol is preferentially utilized by myelinating rat brain in the formation of choline phospholipids having a 1,2-octadecanediol backbone. The D-configuration of the chiral center at carbon-2 of 2-acyl-1,2-alkanediol phosphocholine corresponds to the configuration at carbon-2 of 1,2-diacyl-sn-glycero-3-phosphocholine.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0009-3084
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
17
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
267-74
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:991381-Animals,
pubmed-meshheading:991381-Brain,
pubmed-meshheading:991381-Chromatography, Thin Layer,
pubmed-meshheading:991381-Fatty Acids,
pubmed-meshheading:991381-Fatty Alcohols,
pubmed-meshheading:991381-Hydroxy Acids,
pubmed-meshheading:991381-Molecular Conformation,
pubmed-meshheading:991381-Myelin Sheath,
pubmed-meshheading:991381-Phosphatidylcholines,
pubmed-meshheading:991381-Rats,
pubmed-meshheading:991381-Skin,
pubmed-meshheading:991381-Stereoisomerism,
pubmed-meshheading:991381-Structure-Activity Relationship
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pubmed:year |
1976
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pubmed:articleTitle |
Configurational analysis of long-chain alkanediols.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, U.S. Gov't, Non-P.H.S.
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