Switch to
Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
1977-1-25
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pubmed:abstractText |
The ultrastructure of human placental capillaries was investigated using perfusion fixation and the freeze-fracturing technique. The capillaries have a continuous endothelium especially rich in microfilaments, whereas micropinocytotic vesicles are exceedingly scarce. The endothelial cells are connected by three types of junctions: (1) zonulae occludentes characterized by 2 to 4 focal regions of membrane contact in thin-sectioned specimens and an equal number of ridges on the membrane E-face in freeze-fractured specimens; (2) small gap junctions associated with the zonula occludens. (3) attachment plaques resembling zonulae adhaerentes in their fine structure. Endothelial cells are provided with long, circularly oriented pseudopodial extensions, which may be responsible for intermittent constrictions of the vessel lumen. These findings indicate that diaplacental transport at the level of the fetal capillary is controlled by the cytoplasm of the endothelial cells and probably occurs only to a very limited extent by way of micropinocytotic vesicles.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0302-766X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
14
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pubmed:volume |
172
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
157-69
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:991209-Capillaries,
pubmed-meshheading:991209-Capillary Permeability,
pubmed-meshheading:991209-Cell Membrane,
pubmed-meshheading:991209-Endothelium,
pubmed-meshheading:991209-Female,
pubmed-meshheading:991209-Freeze Fracturing,
pubmed-meshheading:991209-Humans,
pubmed-meshheading:991209-Intercellular Junctions,
pubmed-meshheading:991209-Microscopy, Electron,
pubmed-meshheading:991209-Pinocytosis,
pubmed-meshheading:991209-Placenta,
pubmed-meshheading:991209-Pregnancy,
pubmed-meshheading:991209-Pseudopodia
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pubmed:year |
1976
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pubmed:articleTitle |
Ultrastructure of perfusion-fixed fetal capillaries in the human placenta.
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pubmed:publicationType |
Journal Article
|