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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
1978-10-25
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pubmed:abstractText |
Five lots (100 ml or more) of heterologous antiserums specific for human T lymphocytes were prepared using human or Rhesus monkey thymocytes as immunogens. After appropriate adsorptions, these antiserums reacted by immunofluorescence with 68% of human peripheral blood mononuclear cells and 98% of human thymocytes, with E-rosette--positive cells but not with EAC-rosette--positive cells or five human B-lymphoblastoid-cell lines. Blocking experiments showed that Rhesus monkey thymocytes share thymic antigenic determinant(s) with humans. E-rosette receptors modulated independently from T-cell heteroantigens. Non-E--rosetting neoplastic T cells were identified in several patients with lymphoproliferative malignancies. Applying both the E-rosette assay and the anti-T-cell serum provides a better method of defining the biologic properties of normal and neoplastic T lymphocytes. Standardization of immunofluorescent conjugates for human T- or B-cell enumeration is simplified if large lots of well-characterized antiserums are available.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/99047-1086250,
http://linkedlifedata.com/resource/pubmed/commentcorrection/99047-1086318,
http://linkedlifedata.com/resource/pubmed/commentcorrection/99047-1091657,
http://linkedlifedata.com/resource/pubmed/commentcorrection/99047-126656,
http://linkedlifedata.com/resource/pubmed/commentcorrection/99047-14202251,
http://linkedlifedata.com/resource/pubmed/commentcorrection/99047-190316,
http://linkedlifedata.com/resource/pubmed/commentcorrection/99047-192682,
http://linkedlifedata.com/resource/pubmed/commentcorrection/99047-405531,
http://linkedlifedata.com/resource/pubmed/commentcorrection/99047-4113510,
http://linkedlifedata.com/resource/pubmed/commentcorrection/99047-4114496,
http://linkedlifedata.com/resource/pubmed/commentcorrection/99047-4160044,
http://linkedlifedata.com/resource/pubmed/commentcorrection/99047-4206591,
http://linkedlifedata.com/resource/pubmed/commentcorrection/99047-4266346,
http://linkedlifedata.com/resource/pubmed/commentcorrection/99047-4357682,
http://linkedlifedata.com/resource/pubmed/commentcorrection/99047-4501203,
http://linkedlifedata.com/resource/pubmed/commentcorrection/99047-4541082,
http://linkedlifedata.com/resource/pubmed/commentcorrection/99047-4541574,
http://linkedlifedata.com/resource/pubmed/commentcorrection/99047-4549688,
http://linkedlifedata.com/resource/pubmed/commentcorrection/99047-4561342,
http://linkedlifedata.com/resource/pubmed/commentcorrection/99047-4567307,
http://linkedlifedata.com/resource/pubmed/commentcorrection/99047-4590767,
http://linkedlifedata.com/resource/pubmed/commentcorrection/99047-4995960,
http://linkedlifedata.com/resource/pubmed/commentcorrection/99047-5317457,
http://linkedlifedata.com/resource/pubmed/commentcorrection/99047-5477925,
http://linkedlifedata.com/resource/pubmed/commentcorrection/99047-59778,
http://linkedlifedata.com/resource/pubmed/commentcorrection/99047-6067378,
http://linkedlifedata.com/resource/pubmed/commentcorrection/99047-65428,
http://linkedlifedata.com/resource/pubmed/commentcorrection/99047-71961,
http://linkedlifedata.com/resource/pubmed/commentcorrection/99047-804005,
http://linkedlifedata.com/resource/pubmed/commentcorrection/99047-805205
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0002-9440
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
92
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
619-35
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
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pubmed:year |
1978
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pubmed:articleTitle |
Antiserums for immunofluorescent enumeration of human T lymphocytes utilizing fluoresceinated staphylococcal protein A.
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pubmed:publicationType |
Journal Article
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