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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
1976-11-21
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pubmed:abstractText |
Serum levels of prolactin (PRL), FSH, LH and oestradiol-17 beta were determined by radioimmunoassay in 57 lactating women and in 20 women in whom lactation was inhibited by ergocryptine (CS-154). Women who breast fed their infants exhibited high PRL levels which abruptly declined within 48 h post-partum, and remained low for the duration of the study. Serum FSH was undetectable during the first week post-partum in lactating as well as in CB-154 treated women. Thereafter, lactating women showed increasing FSH levels which reached a maximum by the third week post-partum. These FSH values were higher in lactating women than in the CBS-154 treated group. In contrast, LH levels were higher in those women receiving CB-154. Serum oestradiol-17 beta remained in low levels throughout the study, and no difference was observed between the two groups of subjects. From these results it seems that: 1) inhibition of PRL secretion leads to a faster recovery of gonadotrophin secretion toward the "menstrual type", and 2) PRL suppression produces no effect on the ovarian oestrogen production.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Ergolines,
http://linkedlifedata.com/resource/pubmed/chemical/Estradiol,
http://linkedlifedata.com/resource/pubmed/chemical/Follicle Stimulating Hormone,
http://linkedlifedata.com/resource/pubmed/chemical/Luteinizing Hormone,
http://linkedlifedata.com/resource/pubmed/chemical/Prolactin
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0001-5598
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
83
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
236-42
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:989659-Adolescent,
pubmed-meshheading:989659-Adult,
pubmed-meshheading:989659-Ergolines,
pubmed-meshheading:989659-Estradiol,
pubmed-meshheading:989659-Female,
pubmed-meshheading:989659-Follicle Stimulating Hormone,
pubmed-meshheading:989659-Humans,
pubmed-meshheading:989659-Lactation,
pubmed-meshheading:989659-Luteinizing Hormone,
pubmed-meshheading:989659-Postpartum Period,
pubmed-meshheading:989659-Pregnancy,
pubmed-meshheading:989659-Prolactin,
pubmed-meshheading:989659-Secretory Rate
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pubmed:year |
1976
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pubmed:articleTitle |
Effect of prolactin suppression on gonadotrophic secretion in the puerperium.
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pubmed:publicationType |
Journal Article
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