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pubmed:abstractText |
Tourette's disorder is characterized by chronic fluctuating motor and vocal tics. Despite extensive investigation of the neuropathophysiology of the disorder by a wide array of methodologies, its neurobiochemical substrate is still unclear. Converging evidence, however, suggests a primary role of the dopaminergic system, particularly within the basal ganglia.
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pubmed:affiliation |
Laboratory of Cerebral Metabolism, National Institute of Mental Health, NIH, Bethesda, MD 20892-4030, USA.
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