| pubmed-article:9889034 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:9889034 | lifeskim:mentions | umls-concept:C0031809 | lld:lifeskim |
| pubmed-article:9889034 | lifeskim:mentions | umls-concept:C0229671 | lld:lifeskim |
| pubmed-article:9889034 | lifeskim:mentions | umls-concept:C0677886 | lld:lifeskim |
| pubmed-article:9889034 | lifeskim:mentions | umls-concept:C0003241 | lld:lifeskim |
| pubmed-article:9889034 | lifeskim:mentions | umls-concept:C0220901 | lld:lifeskim |
| pubmed-article:9889034 | lifeskim:mentions | umls-concept:C2347946 | lld:lifeskim |
| pubmed-article:9889034 | pubmed:issue | 1 | lld:pubmed |
| pubmed-article:9889034 | pubmed:dateCreated | 1999-2-22 | lld:pubmed |
| pubmed-article:9889034 | pubmed:abstractText | The objective of this study was to assess the prognostic relevance of preoperative serum anti-p53 antibodies in epithelial ovarian cancer. These autoantibodies were detected with a new generation enzyme-linked immunosorbent assay in blood samples preoperatively drawn from 86 patients with this malignancy. Serum anti-p53 antibodies were found in 3 (10.0%) of the 30 patients with stage I-II and 15 (26.8%) of the 56 patients with stage III-IV epithelial ovarian cancer (P = 0.09). We assessed in detail 44 patients with stage III-IV disease who underwent six cycles of first-line platinum-based chemotherapy. A pathological complete response at second-look was achieved by none of the 15 patients with serum anti-p53 antibodies compared to 24.1% of the 29 patients without autoantibodies (P = 0.09). However, the preoperative serum anti-p53 antibody status had no prognostic relevance for progression-free survival and survival. In conclusion, the assessment of preoperative serum anti-p53 antibodies seems to have a limited clinical value in the management of patients with advanced epithelial ovarian cancer. | lld:pubmed |
| pubmed-article:9889034 | pubmed:language | eng | lld:pubmed |
| pubmed-article:9889034 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9889034 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:9889034 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9889034 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9889034 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:9889034 | pubmed:month | Jan | lld:pubmed |
| pubmed-article:9889034 | pubmed:issn | 0090-8258 | lld:pubmed |
| pubmed-article:9889034 | pubmed:author | pubmed-author:BevilacquaGG | lld:pubmed |
| pubmed-article:9889034 | pubmed:author | pubmed-author:GenazzaniA... | lld:pubmed |
| pubmed-article:9889034 | pubmed:author | pubmed-author:FerdeghiniMM | lld:pubmed |
| pubmed-article:9889034 | pubmed:author | pubmed-author:GadducciAA | lld:pubmed |
| pubmed-article:9889034 | pubmed:author | pubmed-author:Annicchiarico... | lld:pubmed |
| pubmed-article:9889034 | pubmed:author | pubmed-author:FanucchiAA | lld:pubmed |
| pubmed-article:9889034 | pubmed:author | pubmed-author:ButtittaFF | lld:pubmed |
| pubmed-article:9889034 | pubmed:author | pubmed-author:GagettiOO | lld:pubmed |
| pubmed-article:9889034 | pubmed:author | pubmed-author:CosioSS | lld:pubmed |
| pubmed-article:9889034 | pubmed:copyrightInfo | Copyright 1999 Academic Press. | lld:pubmed |
| pubmed-article:9889034 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:9889034 | pubmed:volume | 72 | lld:pubmed |
| pubmed-article:9889034 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:9889034 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:9889034 | pubmed:pagination | 76-81 | lld:pubmed |
| pubmed-article:9889034 | pubmed:dateRevised | 2005-11-17 | lld:pubmed |
| pubmed-article:9889034 | pubmed:meshHeading | pubmed-meshheading:9889034-... | lld:pubmed |
| pubmed-article:9889034 | pubmed:meshHeading | pubmed-meshheading:9889034-... | lld:pubmed |
| pubmed-article:9889034 | pubmed:meshHeading | pubmed-meshheading:9889034-... | lld:pubmed |
| pubmed-article:9889034 | pubmed:meshHeading | pubmed-meshheading:9889034-... | lld:pubmed |
| pubmed-article:9889034 | pubmed:meshHeading | pubmed-meshheading:9889034-... | lld:pubmed |
| pubmed-article:9889034 | pubmed:meshHeading | pubmed-meshheading:9889034-... | lld:pubmed |
| pubmed-article:9889034 | pubmed:meshHeading | pubmed-meshheading:9889034-... | lld:pubmed |
| pubmed-article:9889034 | pubmed:meshHeading | pubmed-meshheading:9889034-... | lld:pubmed |
| pubmed-article:9889034 | pubmed:year | 1999 | lld:pubmed |
| pubmed-article:9889034 | pubmed:articleTitle | Assessment of the prognostic relevance of serum anti-p53 antibodies in epithelial ovarian cancer. | lld:pubmed |
| pubmed-article:9889034 | pubmed:affiliation | Department of Procreative Medicine, Division of Gynecology and Obstetrics, University of Pisa, Via Roma 67, Pisa, 56127, Italy. | lld:pubmed |
| pubmed-article:9889034 | pubmed:publicationType | Journal Article | lld:pubmed |
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