Linked Life Data

9888589

Source:http://linkedlifedata.com/resource/pubmed/id/9888589

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3-4
pubmed:dateCreated
1999-4-13
pubmed:abstractText
We studied the expression of inhibin alpha-subunit in normal and hyperplastic adrenal glands, as well as in various adrenocortical tumors. The protein expression of inhibin alpha was performed by immunohistochemistry. Virilizing adenomas showed strong immunoreactivity against monoclonal inhibin alpha-subunit antibody, whereas other adenomas were only weakly positive or completely negative. In the adrenal cortex no inhibin alpha immunoreactivity was detected in the zona glomerulosa. Zona fasciculata showed weak staining for inhibin alpha, however, strong immunostaining was detected in zona reticularis both in normal and hyperplastic adrenal glands. Adrenal medulla was negative for inhibin alpha. In conclusion, we show high expression of inhibin alpha subunit in zona reticularis of normal and hyperplastic adrenal glands as well as strong expression in virilizing adenomas.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0743-5800
pubmed:author
pubmed:issnType
Print
pubmed:volume
24
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
865-7
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:articleTitle
Expression of inhibin alpha in the human adrenal gland and adrenocortical tumors.
pubmed:affiliation
Haartman Institute, Department of Pathology, University of Helsinki, Finland.
pubmed:publicationType
Journal Article