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rdf:type |
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lifeskim:mentions |
umls-concept:C0017262,
umls-concept:C0035298,
umls-concept:C0078058,
umls-concept:C0185117,
umls-concept:C0205217,
umls-concept:C0205263,
umls-concept:C0242184,
umls-concept:C0442043,
umls-concept:C0475224,
umls-concept:C1256770,
umls-concept:C1428114,
umls-concept:C1707520,
umls-concept:C2911684
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pubmed:issue |
1
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pubmed:dateCreated |
1999-1-20
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pubmed:abstractText |
Hypoxia inducible factor-1 (HIF-1) is a transcription factor composed of HIF-1alpha and HIF-1beta subunits. HIF-1 transactivates multiple genes whose products play key roles in oxygen homeostasis, including vascular endothelial growth factor (VEGF). This study was designed to determine whether HIF-1 levels are increased in ischemic retina and whether there is a correlation with increased expression of VEGF.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/DNA Primers,
http://linkedlifedata.com/resource/pubmed/chemical/DNA-Binding Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Endothelial Growth Factors,
http://linkedlifedata.com/resource/pubmed/chemical/Hif1a protein, mouse,
http://linkedlifedata.com/resource/pubmed/chemical/Hypoxia-Inducible Factor 1,
http://linkedlifedata.com/resource/pubmed/chemical/Hypoxia-Inducible Factor 1, alpha...,
http://linkedlifedata.com/resource/pubmed/chemical/Lymphokines,
http://linkedlifedata.com/resource/pubmed/chemical/Nuclear Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/RNA, Messenger,
http://linkedlifedata.com/resource/pubmed/chemical/Transcription Factors,
http://linkedlifedata.com/resource/pubmed/chemical/Vascular Endothelial Growth Factor A,
http://linkedlifedata.com/resource/pubmed/chemical/Vascular Endothelial Growth Factors
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0146-0404
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pubmed:author |
pubmed-author:CampochiaroP APA,
pubmed-author:DellaNN,
pubmed-author:HackettS FSF,
pubmed-author:LunaJ DJD,
pubmed-author:OkamotoNN,
pubmed-author:OzakiHH,
pubmed-author:OzakiKK,
pubmed-author:SemenzaG LGL,
pubmed-author:YamadaHH,
pubmed-author:YuA YAY,
pubmed-author:ZackD JDJ
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pubmed:issnType |
Print
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pubmed:volume |
40
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
182-9
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:9888442-Aging,
pubmed-meshheading:9888442-Animals,
pubmed-meshheading:9888442-DNA Primers,
pubmed-meshheading:9888442-DNA-Binding Proteins,
pubmed-meshheading:9888442-Endothelial Growth Factors,
pubmed-meshheading:9888442-Hypoxia-Inducible Factor 1,
pubmed-meshheading:9888442-Hypoxia-Inducible Factor 1, alpha Subunit,
pubmed-meshheading:9888442-Immunoblotting,
pubmed-meshheading:9888442-Immunoenzyme Techniques,
pubmed-meshheading:9888442-In Situ Hybridization,
pubmed-meshheading:9888442-Ischemia,
pubmed-meshheading:9888442-Lymphokines,
pubmed-meshheading:9888442-Mice,
pubmed-meshheading:9888442-Mice, Inbred C57BL,
pubmed-meshheading:9888442-Nuclear Proteins,
pubmed-meshheading:9888442-RNA, Messenger,
pubmed-meshheading:9888442-Retinal Diseases,
pubmed-meshheading:9888442-Retinal Vessels,
pubmed-meshheading:9888442-Transcription Factors,
pubmed-meshheading:9888442-Vascular Endothelial Growth Factor A,
pubmed-meshheading:9888442-Vascular Endothelial Growth Factors
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pubmed:year |
1999
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pubmed:articleTitle |
Hypoxia inducible factor-1alpha is increased in ischemic retina: temporal and spatial correlation with VEGF expression.
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pubmed:affiliation |
Department of Ophthalmology, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21287-9277, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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