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rdf:type |
|
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lifeskim:mentions |
umls-concept:C0011065,
umls-concept:C0017262,
umls-concept:C0039194,
umls-concept:C0086418,
umls-concept:C0127400,
umls-concept:C0162638,
umls-concept:C0162871,
umls-concept:C0185117,
umls-concept:C1135918,
umls-concept:C1363844,
umls-concept:C2911684
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|
pubmed:issue |
1
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|
pubmed:dateCreated |
1999-2-10
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|
pubmed:abstractText |
Thinning of the tunica media and rarefaction of smooth muscle cells (SMCs) characterize aneurysmal aortas. Apoptosis determines the cellularity and morphogenesis of tissue. Macrophages and T lymphocytes infiltrate the wall of abdominal aortic aneurysms (AAAs) and produce death-promoting proteins (perforin, Fas, and FasL). This study investigated whether apoptosis occurs in association with the expression of these proteins.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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|
pubmed:citationSubset |
AIM
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pubmed:chemical |
|
|
pubmed:status |
MEDLINE
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|
pubmed:issn |
0009-7322
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pubmed:author |
|
|
pubmed:issnType |
Print
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pubmed:volume |
99
|
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
96-104
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|
pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:9884385-Aged,
pubmed-meshheading:9884385-Aged, 80 and over,
pubmed-meshheading:9884385-Aortic Aneurysm, Abdominal,
pubmed-meshheading:9884385-Apoptosis,
pubmed-meshheading:9884385-Biological Markers,
pubmed-meshheading:9884385-Case-Control Studies,
pubmed-meshheading:9884385-Cell Death,
pubmed-meshheading:9884385-Female,
pubmed-meshheading:9884385-Humans,
pubmed-meshheading:9884385-Immunohistochemistry,
pubmed-meshheading:9884385-In Situ Nick-End Labeling,
pubmed-meshheading:9884385-Leukocytes,
pubmed-meshheading:9884385-Male,
pubmed-meshheading:9884385-Middle Aged,
pubmed-meshheading:9884385-Muscle, Smooth, Vascular,
pubmed-meshheading:9884385-T-Lymphocytes
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|
pubmed:articleTitle |
Death of smooth muscle cells and expression of mediators of apoptosis by T lymphocytes in human abdominal aortic aneurysms.
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pubmed:affiliation |
Cardiovascular Division, Department of Medicine, Vascular Medicine and Atherosclerosis Unit, Brigham and Women's Hospital, Harvard Medical School, Boston, Mass 02115, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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