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rdf:type |
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lifeskim:mentions |
umls-concept:C0017725,
umls-concept:C0027882,
umls-concept:C0030054,
umls-concept:C0032214,
umls-concept:C0034693,
umls-concept:C0034721,
umls-concept:C0035820,
umls-concept:C0037473,
umls-concept:C0205164,
umls-concept:C0205263,
umls-concept:C0600138,
umls-concept:C0871712,
umls-concept:C1816453
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pubmed:issue |
1
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pubmed:dateCreated |
1999-2-8
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pubmed:abstractText |
Striatal spiny neurons are selectively vulnerable to ischemia, but the ionic mechanisms underlying this selective vulnerability are unclear. Although a possible involvement of sodium and calcium ions has been postulated in the ischemia-induced damage of rat striatal neurons, the ischemia-induced ionic changes have never been analyzed in this neuronal subtype.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/1,2-bis(2-aminophenoxy)ethane-N,N,N'...,
http://linkedlifedata.com/resource/pubmed/chemical/Adenosine Triphosphate,
http://linkedlifedata.com/resource/pubmed/chemical/Calcium,
http://linkedlifedata.com/resource/pubmed/chemical/Calcium Channel Blockers,
http://linkedlifedata.com/resource/pubmed/chemical/Calcium Channels,
http://linkedlifedata.com/resource/pubmed/chemical/Chelating Agents,
http://linkedlifedata.com/resource/pubmed/chemical/Egtazic Acid,
http://linkedlifedata.com/resource/pubmed/chemical/Glucose,
http://linkedlifedata.com/resource/pubmed/chemical/Glyburide,
http://linkedlifedata.com/resource/pubmed/chemical/Hypoglycemic Agents,
http://linkedlifedata.com/resource/pubmed/chemical/Magnesium,
http://linkedlifedata.com/resource/pubmed/chemical/Oxygen,
http://linkedlifedata.com/resource/pubmed/chemical/Potassium Channel Blockers,
http://linkedlifedata.com/resource/pubmed/chemical/Potassium Channels,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Glutamate,
http://linkedlifedata.com/resource/pubmed/chemical/Sodium,
http://linkedlifedata.com/resource/pubmed/chemical/Sodium Channel Blockers,
http://linkedlifedata.com/resource/pubmed/chemical/Sodium Channels,
http://linkedlifedata.com/resource/pubmed/chemical/Tetrodotoxin,
http://linkedlifedata.com/resource/pubmed/chemical/Tolbutamide
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0039-2499
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
30
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
171-9
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pubmed:dateRevised |
2010-3-24
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pubmed:meshHeading |
pubmed-meshheading:9880406-Adenosine Triphosphate,
pubmed-meshheading:9880406-Animals,
pubmed-meshheading:9880406-Brain Ischemia,
pubmed-meshheading:9880406-Calcium,
pubmed-meshheading:9880406-Calcium Channel Blockers,
pubmed-meshheading:9880406-Calcium Channels,
pubmed-meshheading:9880406-Cerebral Cortex,
pubmed-meshheading:9880406-Chelating Agents,
pubmed-meshheading:9880406-Corpus Striatum,
pubmed-meshheading:9880406-Egtazic Acid,
pubmed-meshheading:9880406-Glucose,
pubmed-meshheading:9880406-Glyburide,
pubmed-meshheading:9880406-Hypoglycemic Agents,
pubmed-meshheading:9880406-Magnesium,
pubmed-meshheading:9880406-Membrane Potentials,
pubmed-meshheading:9880406-Neurons,
pubmed-meshheading:9880406-Organ Culture Techniques,
pubmed-meshheading:9880406-Oxygen,
pubmed-meshheading:9880406-Patch-Clamp Techniques,
pubmed-meshheading:9880406-Potassium Channel Blockers,
pubmed-meshheading:9880406-Potassium Channels,
pubmed-meshheading:9880406-Rats,
pubmed-meshheading:9880406-Rats, Wistar,
pubmed-meshheading:9880406-Receptors, Glutamate,
pubmed-meshheading:9880406-Sodium,
pubmed-meshheading:9880406-Sodium Channel Blockers,
pubmed-meshheading:9880406-Sodium Channels,
pubmed-meshheading:9880406-Tetrodotoxin,
pubmed-meshheading:9880406-Tolbutamide
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pubmed:year |
1999
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pubmed:articleTitle |
Sodium influx plays a major role in the membrane depolarization induced by oxygen and glucose deprivation in rat striatal spiny neurons.
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pubmed:affiliation |
Clinical Neurologica, Dip. Neuroscienze, Università di Roma Tor Vergata, Rome, Italy.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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