|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0005767,
umls-concept:C0018787,
umls-concept:C0018791,
umls-concept:C0022116,
umls-concept:C0035124,
umls-concept:C0039005,
umls-concept:C0040732,
umls-concept:C0297112,
umls-concept:C0332256,
umls-concept:C0445103,
umls-concept:C0597484,
umls-concept:C0678640,
umls-concept:C1442458,
umls-concept:C1512335,
umls-concept:C1999216,
umls-concept:C2587213
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pubmed:issue |
6
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pubmed:dateCreated |
1999-3-11
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pubmed:abstractText |
The aim of our study was to develop a surgical technique for a successful transplantation of hearts harvested after 30 min of normothermic ischemia without donor pretreatment. Successful transplantation of ischemic compromised hearts could help to expand the severely limited donor pool. We used the pig model because this species is very susceptible to myocardial ischemia. Na+-H+-exchange (NHE) inhibitors have shown excellent protective properties in several in vitro and in vivo models of myocardial ischemia and reperfusion.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
1010-7940
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pubmed:author |
|
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pubmed:issnType |
Print
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pubmed:volume |
14
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
607-14
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:9879873-Animals,
pubmed-meshheading:9879873-Blood,
pubmed-meshheading:9879873-Cardioplegic Solutions,
pubmed-meshheading:9879873-Creatine Kinase,
pubmed-meshheading:9879873-Guanidines,
pubmed-meshheading:9879873-Heart Arrest, Induced,
pubmed-meshheading:9879873-Heart Transplantation,
pubmed-meshheading:9879873-Isoenzymes,
pubmed-meshheading:9879873-L-Lactate Dehydrogenase,
pubmed-meshheading:9879873-Myocardial Reperfusion,
pubmed-meshheading:9879873-Myocardial Reperfusion Injury,
pubmed-meshheading:9879873-Sodium-Hydrogen Antiporter,
pubmed-meshheading:9879873-Stroke Volume,
pubmed-meshheading:9879873-Sulfones,
pubmed-meshheading:9879873-Swine,
pubmed-meshheading:9879873-Time Factors
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pubmed:year |
1998
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pubmed:articleTitle |
Orthotopic transplantation of pig hearts harvested after 30 min of normothermic ischemia: controlled reperfusion with blood cardioplegia containing the Na+-H+-exchange inhibitor HOE 642.
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pubmed:affiliation |
Department of Cardiovascular Surgery, Albert-Ludwigs-University Medical Center, Freiburg, Germany.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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