|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
2
|
|
pubmed:dateCreated |
1999-3-23
|
|
pubmed:abstractText |
We studied the pattern of human antiganglioside antibody reactivities causing an acute conduction block in rat myelinated nerve fibers, using an in vitro preparation of the sciatic-tibial nerve. With the aid of complements, IgM antibodies reacting with the terminal disaccharide of galactose (beta1-3)N-acetylgalactosamine produced the block. These findings may help us to understand the mechanism in which the conduction block occurs in neuropathies associated with antiganglioside antibodies.
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Dec
|
|
pubmed:issn |
0022-510X
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:day |
11
|
|
pubmed:volume |
161
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
163-8
|
|
pubmed:dateRevised |
2006-11-15
|
|
pubmed:meshHeading |
pubmed-meshheading:9879698-Action Potentials,
pubmed-meshheading:9879698-Adolescent,
pubmed-meshheading:9879698-Adult,
pubmed-meshheading:9879698-Animals,
pubmed-meshheading:9879698-Antigen-Antibody Reactions,
pubmed-meshheading:9879698-Demyelinating Diseases,
pubmed-meshheading:9879698-Evoked Potentials,
pubmed-meshheading:9879698-Female,
pubmed-meshheading:9879698-Gangliosides,
pubmed-meshheading:9879698-Humans,
pubmed-meshheading:9879698-Male,
pubmed-meshheading:9879698-Middle Aged,
pubmed-meshheading:9879698-Nerve Block,
pubmed-meshheading:9879698-Nerve Fibers, Myelinated,
pubmed-meshheading:9879698-Neural Conduction,
pubmed-meshheading:9879698-Radiculopathy,
pubmed-meshheading:9879698-Rats,
pubmed-meshheading:9879698-Rats, Wistar
|
|
pubmed:year |
1998
|
|
pubmed:articleTitle |
The pattern of antiganglioside antibody reactivities producing myelinated nerve conduction block in vitro.
|
|
pubmed:affiliation |
Department of Neurology, NTT Kanto Teishin Hospital, Tokyo, Japan. arasaki@kth.ntt.co.jp
|
|
pubmed:publicationType |
Journal Article,
Clinical Trial,
In Vitro,
Controlled Clinical Trial
|
