Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
|
pubmed:dateCreated |
1999-2-23
|
pubmed:abstractText |
Patchy fur is a semidominant X-linked mutation in the mouse, resulting in a sparse coat. The Paf mutation also alters the normal segregation of the X and the Y chromosomes during male meiosis by causing nondisjunction at anaphase I. Analysis of 1139 female meioses from an intersubspecific backcross using 15 PCR-based markers localizes Paf to an approximately 0.2-cM interval that includes the pseudoautosomal boundary. The meiotic nondisjunction phenotype may result from a chromosomal rearrangement that includes pseudoautosomal sequences and affects XY pairing.
|
pubmed:grant | |
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Dec
|
pubmed:issn |
0888-7543
|
pubmed:author | |
pubmed:copyrightInfo |
Copyright 1998 Academic Press.
|
pubmed:issnType |
Print
|
pubmed:day |
15
|
pubmed:volume |
54
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
556-9
|
pubmed:dateRevised |
2007-11-14
|
pubmed:meshHeading |
pubmed-meshheading:9878259-Animals,
pubmed-meshheading:9878259-Chromosome Mapping,
pubmed-meshheading:9878259-Chromosomes, Artificial, Yeast,
pubmed-meshheading:9878259-Contig Mapping,
pubmed-meshheading:9878259-Crosses, Genetic,
pubmed-meshheading:9878259-DNA Primers,
pubmed-meshheading:9878259-Female,
pubmed-meshheading:9878259-Genetic Markers,
pubmed-meshheading:9878259-Hair,
pubmed-meshheading:9878259-Male,
pubmed-meshheading:9878259-Mice,
pubmed-meshheading:9878259-Mice, Inbred Strains,
pubmed-meshheading:9878259-Mice, Mutant Strains,
pubmed-meshheading:9878259-Mutation,
pubmed-meshheading:9878259-Polymorphism, Genetic,
pubmed-meshheading:9878259-X Chromosome
|
pubmed:year |
1998
|
pubmed:articleTitle |
Patchy fur, a mouse coat mutation associated with X-Y nondisjunction, maps to the pseudoautosomal boundary region.
|
pubmed:affiliation |
Molecular Biology Program, University of Southern California, Los Angeles, California, 90089-1340, USA.
|
pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, U.S. Gov't, Non-P.H.S.
|