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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
20
|
| pubmed:dateCreated |
1999-2-2
|
| pubmed:abstractText |
Prooligonucleotides with alternating S-Acyl-ThioEthyl (SATE) phosphotriester and phosphodiester linkages or a gap were synthesized by elimination of cyanoethyl group with non-nucleophilic base DBU. Their half-lives in the presence of Pig Liver Esterases (PLE) and in total cell extract were determined.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Oct
|
| pubmed:issn |
0960-894X
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:day |
20
|
| pubmed:volume |
8
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
2913-8
|
| pubmed:dateRevised |
2006-11-15
|
| pubmed:meshHeading |
pubmed-meshheading:9873647-Animals,
pubmed-meshheading:9873647-Cell Extracts,
pubmed-meshheading:9873647-Esterases,
pubmed-meshheading:9873647-Half-Life,
pubmed-meshheading:9873647-Liver,
pubmed-meshheading:9873647-Oligonucleotides,
pubmed-meshheading:9873647-Swine,
pubmed-meshheading:9873647-Thymidine
|
| pubmed:year |
1998
|
| pubmed:articleTitle |
First synthesis of alternating SATE-phosphotriester/phosphodiester prooligonucleotides on solid support.
|
| pubmed:affiliation |
Laboratoire de Chimie Bio-Organique, UMR 5625, Université de Montpellier II, France.
|
| pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|