9873600

Source:http://linkedlifedata.com/resource/pubmed/id/9873600

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0021467, umls-concept:C0021469, umls-concept:C0039736, umls-concept:C0243071
pubmed:issue	19
pubmed:dateCreated	1999-2-2
pubmed:abstractText	N-Phthaloyl 3-amino-3-arylpropionic acid analogs of thalidomide that are potent inhibitors of tumor necrosis factor-alpha are reported. These compounds were found to be potent inhibitors of phosphodiesterase 4.
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/9107377
pubmed:citationSubset	IM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/3',5'-Cyclic-AMP Phosphodiesterases, http://linkedlifedata.com/resource/pubmed/chemical/Cyclic Nucleotide..., http://linkedlifedata.com/resource/pubmed/chemical/Lipopolysaccharides, http://linkedlifedata.com/resource/pubmed/chemical/Phosphodiesterase Inhibitors, http://linkedlifedata.com/resource/pubmed/chemical/Thalidomide, http://linkedlifedata.com/resource/pubmed/chemical/Tumor Necrosis Factor-alpha
pubmed:status	MEDLINE
pubmed:month	Oct
pubmed:issn	0960-894X
pubmed:author	pubmed-author:ChenYY, pubmed-author:CorralL GLG, pubmed-author:MichalováCC, pubmed-author:MundenB JBJ, pubmed-author:PattersonR TRT, pubmed-author:ShireM GMG, pubmed-author:WongL MLM
pubmed:issnType	Print
pubmed:day	6
pubmed:volume	8
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	2669-74
pubmed:dateRevised	2007-11-15
pubmed:meshHeading	pubmed-meshheading:9873600-3',5'-Cyclic-AMP Phosphodiesterases, pubmed-meshheading:9873600-Cyclic Nucleotide Phosphodiesterases, Type 4, pubmed-meshheading:9873600-Humans, pubmed-meshheading:9873600-Leukocytes, Mononuclear, pubmed-meshheading:9873600-Lipopolysaccharides, pubmed-meshheading:9873600-Phosphodiesterase Inhibitors, pubmed-meshheading:9873600-Structure-Activity Relationship, pubmed-meshheading:9873600-Thalidomide, pubmed-meshheading:9873600-Tumor Cells, Cultured, pubmed-meshheading:9873600-Tumor Necrosis Factor-alpha
pubmed:year	1998
pubmed:articleTitle	Thalidomide analogs and PDE4 inhibition.
pubmed:affiliation	Celgene Corporation, Warren, NJ 07059 USA.
pubmed:publicationType	Journal Article