9873598

Source:http://linkedlifedata.com/resource/pubmed/id/9873598

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0205314, umls-concept:C0205460, umls-concept:C0205549, umls-concept:C0220781, umls-concept:C0441655, umls-concept:C0596434, umls-concept:C0679622, umls-concept:C1513016, umls-concept:C1883254
pubmed:issue	19
pubmed:dateCreated	1999-2-2
pubmed:abstractText	A novel series of diazepine-based hydroxamic acid inhibitors of MMP-1, MMP-9, and MMP-13 were prepared and evaluated both in vitro and in vivo.
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/9107377
pubmed:citationSubset	IM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/Antineoplastic Agents, http://linkedlifedata.com/resource/pubmed/chemical/Azepines, http://linkedlifedata.com/resource/pubmed/chemical/CGS 27023A, http://linkedlifedata.com/resource/pubmed/chemical/Collagenases, http://linkedlifedata.com/resource/pubmed/chemical/Enzyme Inhibitors, http://linkedlifedata.com/resource/pubmed/chemical/Hydroxamic Acids, http://linkedlifedata.com/resource/pubmed/chemical/Matrix Metalloproteinase 1, http://linkedlifedata.com/resource/pubmed/chemical/Matrix Metalloproteinase 9, http://linkedlifedata.com/resource/pubmed/chemical/Organic Chemicals, http://linkedlifedata.com/resource/pubmed/chemical/Protease Inhibitors, http://linkedlifedata.com/resource/pubmed/chemical/Pyrazines, http://linkedlifedata.com/resource/pubmed/chemical/Sulfonamides, http://linkedlifedata.com/resource/pubmed/chemical/prinomastat
pubmed:status	MEDLINE
pubmed:month	Oct
pubmed:issn	0960-894X
pubmed:author	pubmed-author:AlbrightJ DJD, pubmed-author:DiJosephJ FJF, pubmed-author:KillarL MLM, pubmed-author:LevinJ IJI, pubmed-author:RothC ECE, pubmed-author:SharrM AMA, pubmed-author:SkotnickiJ SJS, pubmed-author:SundBB, pubmed-author:WalterTT
pubmed:issnType	Print
pubmed:day	6
pubmed:volume	8
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	2657-62
pubmed:dateRevised	2006-11-15
pubmed:meshHeading	pubmed-meshheading:9873598-Animals, pubmed-meshheading:9873598-Antineoplastic Agents, pubmed-meshheading:9873598-Azepines, pubmed-meshheading:9873598-Collagenases, pubmed-meshheading:9873598-Enzyme Inhibitors, pubmed-meshheading:9873598-Hydroxamic Acids, pubmed-meshheading:9873598-Matrix Metalloproteinase 1, pubmed-meshheading:9873598-Matrix Metalloproteinase 9, pubmed-meshheading:9873598-Mice, pubmed-meshheading:9873598-Organic Chemicals, pubmed-meshheading:9873598-Protease Inhibitors, pubmed-meshheading:9873598-Pyrazines, pubmed-meshheading:9873598-Structure-Activity Relationship, pubmed-meshheading:9873598-Sulfonamides
pubmed:year	1998
pubmed:articleTitle	The synthesis and biological activity of a novel series of diazepine MMP inhibitors.
pubmed:affiliation	Wyeth-Ayerst Research, Pearl River, NY 10965, USA.
pubmed:publicationType	Journal Article