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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
16
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pubmed:dateCreated |
1999-1-28
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pubmed:abstractText |
Problems were encountered during attempts to prepare N-terminal cysteine-substituted peptide nucleic acids (PNAs) from commercially available, Fmoc-protected monomers. These problems have been surmounted by the use of an S-t-butylmercapto protecting group on the cysteine moiety. The solid-phase syntheses are carried out via a simplified procedure which should be generally useful for manual PNA synthesis.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0960-894X
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
18
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pubmed:volume |
8
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2231-4
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:9873519-Base Sequence,
pubmed-meshheading:9873519-Chromatography, High Pressure Liquid,
pubmed-meshheading:9873519-Cysteine,
pubmed-meshheading:9873519-Indicators and Reagents,
pubmed-meshheading:9873519-Oligodeoxyribonucleotides,
pubmed-meshheading:9873519-Peptide Nucleic Acids,
pubmed-meshheading:9873519-Resins, Plant,
pubmed-meshheading:9873519-Spectrometry, Mass, Matrix-Assisted Laser...
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pubmed:year |
1998
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pubmed:articleTitle |
A simple procedure for solid-phase synthesis of peptide nucleic acids with N-terminal cysteine.
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pubmed:affiliation |
Department of Biochemistry and Molecular Biology, University of Arkansas for Medical Sciences, Little Rock 72205, USA.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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